1762-68-1

Usage

Biological activities

antimicrobial, antiviral, anticancer
Inhibits growth of cancer cell lines
Potential anti-tumor agent
Antiviral activity against herpes simplex virus
Inhibits viral replication
Valuable compound for medicinal chemistry research and drug development

Upstream product

• 10606-73-2 ethyl 2-chloro-2-phenylacetate 
• 17356-08-0 thiourea 
• 43091-22-1 2-phenylthiazolo<3.2-a>pyrimidinium 3-oxide 
• 62-53-3 aniline 
• 37167-62-7 bromo-phenyl-acetic acid methyl ester 
• 67-66-3 chloroform 
• 100-52-7 benzaldehyde 
• 2000-43-3 2,2,2-trichloro-1-phenylethanol 
• 103-82-2 phenylacetic acid 
• 19078-72-9 bromo(phenyl)acetyl chloride 
• 103-80-0 phenylacetyl chloride 

Downstream Products

• 93013-62-8 2-benzylamino-5-phenyl-thiazol-4-one 
• 57260-49-8 5-phenyl-2-(4-p-tolyl-piperazin-1-yl)-thiazol-4-one 
• 1762-63-6 2-dimethylamino-5-phenyl-thiazolin-4-one 
• 57260-50-1 1-[3-(4-methoxy-phenyl)-acryloyl]-4-(4-oxo-5-phenyl-4,5-dihydro-thiazol-2-yl)-piperazine 
• 4695-17-4 5-phenyl-thiazolidine-2,4-dione 
• 4695-09-4 α-mercaptophenylacetic acid 

Relevant academic research and scientific papers

Reeve's synthesis of 2-imino-4-thiazolidinone from alkyl (aryl) trichloromethylcarbinol revisited, a three-component process from aldehyde, chloroform and thiourea

An efficient synthesis of 2-imino-4-thiazolidinones from readily accessible alkyl (aryl) trichloromethylcarbinols and thioureas under mild conditions is reported. A one-pot three-component synthesis of the title compounds from aldehyde, chloroform and thiourea is also developed for the first time

MESOIONIC COMPOUNDS WITH A BRIDGED NITROGEN ATOM. 7. INVESTIGATION OF THE CYCLIZATION OF (2-PYRIMIDINYLTHIO)PHENYLACETIC ACIDS

It is shown that mesoionic thiazolopyrimidines are formed by the action of acetic anhydride on (2-pyrimidinylthio)phenylacetic acids.The structures of these products were established, and their reactions with nucleophilic and electrophilic reagents were studied.