17635-45-9

Basic information

• Product Name: 4-(1H-Pyrazol-1-yl)aniline
• Synonyms: CHEMBRDG-BB 4102901;BUTTPARK 98\50-47;1-(4-AMINOPHENYL)PYRAZOLE;4-PYRAZOL-1-YL-PHENYLAMINE;4-PYRAZOL-1-YL-PHENYLAMINE HCL;4-PYRAZOL-1-YL-PHENYLAMINE HYDROCHLORIDE;4-(1H-PYRAZOL-1-YL)ANILINE;AKOS B029459
• CAS NO: 17635-45-9
• Molecular Formula: C₉H₉N₃
• Molecular Weight: 159.19
• Product Categories: Amines and Anilines;Heterocycles
• Mol File: 17635-45-9.mol
• Article Data: 24

Chemical Properties

• Melting Point: 54 °C
• Boiling Point: 311.978 °C at 760 mmHg
• Flash Point: 142.479 °C
• Appearance: /
• Density: 1.2 g/cm³
• Vapor Pressure: 0.000545mmHg at 25°C
• Refractive Index: 1.641
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 4.03±0.10(Predicted)
• CAS DataBase Reference: 4-(1H-Pyrazol-1-yl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1H-Pyrazol-1-yl)aniline(17635-45-9)
• EPA Substance Registry System: 4-(1H-Pyrazol-1-yl)aniline(17635-45-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39-37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 17635-45-9(Hazardous Substances Data)

Usage

General Description

4-(1H-Pyrazol-1-yl)aniline, also known as 4-pyrazolylaniline, is an organic compound with the chemical formula C9H8N4. It consists of a pyrazole ring attached to an aniline group. This chemical is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and dyes. It is also utilized in the production of rubber chemicals and UV stabilizers. 4-(1H-Pyrazol-1-yl)aniline is considered to be a hazardous chemical and should be handled with caution due to its potential for causing irritation to the skin, eyes, and respiratory system. Furthermore, it may pose environmental risks if not properly managed.

InChI:InChI=1/C9H9N3/c10-8-2-4-9(5-3-8)12-7-1-6-11-12/h1-7H,10H2

Upstream product

• 3463-30-7 1-(4-nitrophenyl)pyrazole 
• 288-13-1 NH-pyrazole 
• 106-40-1 4-bromo-aniline 
• 636-98-6 p-nitrobenzene iodide 
• 106-47-8 4-chloro-aniline 
• 1126-00-7 1-phenylpyrazole 
• 100-16-3 4-nitrophenylhydrazone 
• 350-46-9 4-Fluoronitrobenzene 
• 540-37-4 p-aminoiodobenzene 

Downstream Products

• 16209-02-2 4-(pyrazol-1-yl)-phenol 

Relevant articles and documents

Solvent-free preparation of tris-pyrazolyl-1,3,5-triazines

Tris-pyrazolyl-1,3,5-triazines have been prepared by cyclotrimerization of aromatic nitriles in solvent-free conditions. The interesting structures of these compounds make them candidates for application in coordination chemistry and crystal engineering.

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QUINOLINONE LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF

Described herein are compounds that are LOXL2 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders a

Carbon nitride supported palladium nanoparticles: An active system for the reduction of aromatic nitro-compounds

Synthesis of carbon nitride supported highly dispersed ultrafine palladium nanoparticles has been reported for the reduction of aromatic nitro-compounds using hydrazine hydrate as a reducing agent. As a demonstration, the as-synthesized carbon nitride-palladium composite was shown to be a highly active and chemo-selective for the title reaction. Utilizing the optimized reaction conditions a set of aromatic nitro compounds have been converted to their corresponding amine derivatives with good to excellent yield ranging from 80% to 99%. The catalyst can be used for multiple times without affecting the catalytic performance and can also be stored for a long time at ambient condition maintaining the high catalytic efficiency.