1795-80-8

Basic information

• Product Name: Benzoic acid, 2,4,6-trimethyl-, 1,1-dimethylethyl ester
• CAS NO: 1795-80-8
• Molecular Formula: C14H20O2
• Molecular Weight: 220.312
• Mol File: 1795-80-8.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2,4,6-trimethyl-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2,4,6-trimethyl-, 1,1-dimethylethyl ester(1795-80-8)
• EPA Substance Registry System: Benzoic acid, 2,4,6-trimethyl-, 1,1-dimethylethyl ester(1795-80-8)

Safety Data

• Hazardous Substances Data: 1795-80-8(Hazardous Substances Data)

Usage

General Description

Benzoic acid, 2,4,6-trimethyl-, 1,1-dimethylethyl ester, also known as tert-Butyl 2,4,6-trimethylbenzoate, is a chemical compound commonly used as a fragrance ingredient and flavoring agent in the food industry. It is a colorless liquid with a sweet, fruity odor and is often added to various consumer products such as perfumes, cosmetics, and air fresheners. This chemical is also utilized in the production of plastics, adhesives, and coatings. Additionally, it is used as a solvent in the manufacturing of pharmaceuticals and as an intermediate in the synthesis of other organic compounds. However, it is important to handle this chemical with care, as it can cause irritation to the skin, eyes, and respiratory system if not used properly.

Upstream product

• 480-63-7 mesitylenecarboxylic acid 
• 75-65-0 tert-butyl alcohol 
• 67958-02-5 Mesitoyl bromide 
• 865-47-4 potassium tert-butylate 
• 83766-88-5 2-tert-butoxypyridine 
• 938-18-1 mesitylene-2-carboxylic acid chloride 
• 1450732-56-5 N-tert-butoxy-2,4,6-trimethylbenzamide 
• 81787-27-1 S-2-pyridyl 2,4,6-trimethylbenzothioate 
• 63540-63-6 2-pyridyl mesitoate 
• 2282-84-0 methyl 2,4,6-trimethylbenzoate 

Downstream Products

• 1634-04-4 tert-butyl methyl ether 
• 480-63-7 mesitylenecarboxylic acid 
• 938-18-1 mesitylene-2-carboxylic acid chloride 
• 75980-60-8 (2,4,6-trimethylbenzoyl)diphenylphosphine oxide 
• 253185-03-4 tert-butylbenzene 

Relevant articles and documents

The Chemistry of Acylgermanes: Triacylgermenolates Represent Valuable Building Blocks for the Synthesis of a Variety of Germanium-Based Photoinitiators

The formation of a stable triacylgermenolate 2 as a decisive intermediate was achieved by using three pathways. The first two methods involve the reaction of KOtBu or alternatively potassium with tetraacylgermane 1 yielding 2 via one electron transfer. The mechanism involves the formation of radical anions (shown by EPR). This reaction is highly efficient and selective. The third method is a classical salt metathesis reaction toward 2 in nearly quantitative yield. The formation of 2 was confirmed by NMR spectroscopy, UV-vis measurements, and X-ray crystallography. Germenolate 2 serves as a starting point for a wide variety of organo-germanium compounds. We demonstrate the potential of this intermediate by introducing new types of Ge-based photoinitiators 4b-4f. The UV-vis absorption spectra of 4b-4f show considerably increased band intensities due to the presence of eight or more chromophores. Moreover, compounds 4d-4f show absorption tailing up to 525 nm. The performance of these photoinitiators is demonstrated by spectroscopy (time-resolved EPR, laser flash photolysis (LFP), photobleaching (UV-vis)) and photopolymerization experiments (photo-DSC measurements).

Direct conversion of N -alkoxyamides to carboxylic esters through tandem nbs-mediated oxidative homocoupling and thermal denitrogenation

Treatment of N-alkoxyamides with NBS in toluene was found to conveniently afford the corresponding carboxylic esters, including those bearing a bulky or long-chain substituent, in satisfactory to excellent yields. This approach not only represents a convenient and economic approach to a direct transformation of an alkoxyamide moiety into the carboxylic ester functional group, via oxidative homocoupling and the subsequent thermal denitrogenation, but also facilitates the synthesis of sterically hindered carboxylic esters.

Activated Basic Alumina Promotes a Mild, Clean and High-Yield Racemization-Free Synthesis of t-Butyl Esters from Chiral Acid Bromides and t-Butyl Alcohol

Esterification of a variety of acid bromides having even steric bulkiness with t-BuOH/activated basic alumina gave the corresponding t-butyl esters in good to excellent yields.In the case of chiral acid bromides, no racemization has been ascertained for the first time.