17951-22-3

Basic information

• Product Name: 1,2-ETHANEDIOL, 1-(P-FLUOROPHENYL)-
• Synonyms: 1,2-ETHANEDIOL, 1-(P-FLUOROPHENYL)-;1-(4-fluorophenyl)-1,2-ethanediol
• CAS NO: 17951-22-3
• Molecular Formula: C₈H₉FO₂
• Molecular Weight: 0
• Mol File: 17951-22-3.mol
• Article Data: 24

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,2-ETHANEDIOL, 1-(P-FLUOROPHENYL)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-ETHANEDIOL, 1-(P-FLUOROPHENYL)-(17951-22-3)
• EPA Substance Registry System: 1,2-ETHANEDIOL, 1-(P-FLUOROPHENYL)-(17951-22-3)

Safety Data

• Hazardous Substances Data: 17951-22-3(Hazardous Substances Data)

Upstream product

• 18511-62-1 4-fluorostyrene oxide 
• 124-38-9 carbon dioxide 
• 62-53-3 aniline 
• 766-98-3 1-ethynyl-4-fluorobenzene 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 403-32-7 (4-fluorophenyl)glyoxal 
• 405-99-2 para-fluorostyrene 
• 403-31-6 4-fluoro-2-hydroxy-acetophenone 
• 32222-45-0 4-fluoromandelic acid 
• 156276-23-2 methyl (p-fluorobenzoyl)formate 

Downstream Products

• 1580-83-2 paraflutizide 
• 14471-83-1 3-(4-fluoro-benzyl)-1,1-dioxo-6-trifluoromethyl-1,2,3,4-tetrahydro-1λ⁶-benzo[1,2,4]thiadiazine-7-sulfonic acid amide 
• 59363-31-4 1-[2-(4-chloro-phenyl)-4-(4-fluoro-phenyl)-[1,3]dioxolan-2-ylmethyl]-1H-imidazole 
• 59363-63-2 1-[2-(4-bromo-phenyl)-4-(4-fluoro-phenyl)-[1,3]dioxolan-2-ylmethyl]-1H-imidazole 
• 59365-39-8 2-Bromomethyl-2-(4-bromo-phenyl)-4-(4-fluoro-phenyl)-[1,3]dioxolane 
• 387337-81-7 4-(4-fluoro-phenyl)-2-phenyl-[1,3]dioxolane 
• 459-57-4 4-fluorobenzaldehyde 
• 1256573-66-6 2-hydroxy-2-(4-fluorophenyl)ethyl acetate 
• 1251567-11-9 4-(4-fluorophenyl)-1,3-dioxolan-2-one 
• 213479-90-4 (S)-(+)-1-(4-fluorophenyl)-1,2-ethanediol 
• 179694-35-0 (R)-(-)-1-(4-fluorophenyl)-1,2-ethanediol 

Relevant articles and documents

Asymmetric ring opening of racemic epoxides for enantioselective synthesis of (S)-β-amino alcohols by a cofactor self-sufficient cascade biocatalysis system

A novel one-pot epoxide hydrolase/alcohol dehydrogenase/transaminase cascade process for the asymmetric ring opening of racemic epoxides to enantiopure β-amino alcohols is reported. The product (S)-β-amino alcohols were obtained in 97-99% ee and 79-99% conversion from readily available racemic epoxides.

Catalytic Diastereo- and Enantioconvergent Synthesis of Vicinal Diamines from Diols through Borrowing Hydrogen

We present herein an unprecedented diastereoconvergent synthesis of vicinal diamines from diols through an economical, redox-neutral process. Under cooperative ruthenium and Lewis acid catalysis, readily available anilines and 1,2-diols (as a mixture of diastereomers) couple to forge two C?N bonds in an efficient and diastereoselective fashion. By identifying an effective chiral iridium/phosphoric acid co-catalyzed procedure, the first enantioconvergent double amination of racemic 1,2-diols has also been achieved, resulting in a practical access to highly valuable enantioenriched vicinal diamines.

Visible light induced redox neutral fragmentation of 1,2-diol derivatives

A homogeneous, redox-neutral photo fragmentation of diol derivatives was developed. Under photo/hydrogen atom transfer (HAT) dual catalysis, diol derivatives such as lignin model compounds and diol monoesters undergo selective β C(sp3)-O bond cleavage to afford ketones, phenols and acids effectively.