17983-63-0Relevant academic research and scientific papers
A versatile tandem retro-[ 1,4]-Brook rearrangement-condensation reaction of o-bromoacetophenone silyl enol ethers
Comanita, Bogdan M.,Woo, Simon,Fallis, Alex G.
, p. 5283 - 5286 (1999)
The retro-[1,4]-Brook rearrangement (also referred to as the West or silyl-Wittig rearrangement) has been employed with acetophenone silyl enol ethers to allow regiospecific migration of the silicon from oxygen to the ortho position of the aromatic ring.
Palladium-Catalyzed ortho-C(sp2)-H Silylation of Aromatic Ketones Using an Aminooxyamide Auxiliary
Li, Jianhua,Ding, Meiying,Jiang, Chao
, p. 9036 - 9040 (2021/11/24)
A palladium-catalyzed direct and selective ortho-C(sp2)-H silylation of aromatic ketones has been achieved using an aminooxyamide auxiliary. The reaction tolerates various orth-, meta-, and para- substituents on the aromatic ring and can be applied to thi
Copper-Free Double Silylation of 1,2-Dibromobenzenes Using a Mg/LiCl/DMI System
Kitamura, Tsugio,Yamada, Rin,Gondo, Keisuke,Eguchi, Nobuo,Oyamada, Juzo
, p. 2495 - 2500 (2017/05/22)
The reaction of 1,2-dibromobenzenes with chlorotrimethylsilane efficiently proceeded in the presence of Mg and LiCl in DMI under mild conditions, giving 1,2-bis(trimethylsilyl)benzenes in good to high yields. The reaction of 1,2-dibromobenzenes with chlorodimethylsilane under the same conditions afforded the corresponding 1,2-bis(dimethylsilyl)benzenes in high yields. Functional group transformations of 1,2-bis(trimethylsilyl)benzene were conducted to demonstrate the synthetic utility.
