17997-33-0Relevant academic research and scientific papers
Synthesis of new functionalized mono- and diphosphonic acids with five-membered aza-heterocycles moieties
Prishchenko, Andrey A.,Alekseyev, Roman S.,Livantsov, Mikhail V.,Novikova, Olga P.,Livantsova, Ludmila I.,Terenin, Vladimir I.,Petrosyan, Valery S.
, (2017)
The new functionalized hydroxymethylphosphonic and methylenediphosphonic acids are synthesized via unique reaction of tris(trimethylsilyl)phosphite and N-formyl derivatives of five-membered aza-heterocycles at the presence of effective catalyst—trimethylsilyl triflate.
New functionalized derivatives of mono- and diphosphonic acids substituted with five-membered nitrogen heterocycles
Prishchenko,Livantsov,Novikova,Livantsova,Alekseyev,Terenin,Petrosyan
, p. 342 - 345 (2017)
New types of (hydroxymethyl)phosphonic and (methylene)diphosphonic acids bearing heterocyclic fragments were synthesized by addition of tris(trimethylsilyl) phosphite to N-formyl derivatives of five-membered nitrogen heterocycles.
Reaction of P(III) chlorides with aldehydes: II. Reaction of primary intermediates with aprotic nucleophiles: Ethylene oxide, acetals, trialkyl orthoformates, and trialkyl phosphites
Gazizov,Khairullin,Karimova
, p. 2293 - 2300 (2014/03/21)
Structure of primary intermediates of the reaction of P(III) chlorides with aliphatic aldehydes was confirmed by their reactions with such aprotic reagents like ethylene oxide, trialkyl phosphites, acetals, and trialkyl orthoformates. Principle difference
Synthesis of phosphorus-substituted dialkylamides of organophosphorus acids, containing P-C-N-P Moiety
Prishchenko, Andrey A.,Livantsov, Mikhail V.,Novikova, Olga P.,Livantsova, Ludmila I.,Petrosyan, Valery S.
, p. 495 - 499 (2008/12/21)
Reactions of N-(trimethylsilyl)amino-methylphosphonates with organophosphorus acid chlorides were studied, which allowed to develop convenient synthetic approaches to novel phosphorus-substituted dialkylamides of organophosphorus acids, including a P-C-N-P moiety. Certain properties of the resulting compounds are presented.
Synthesis of phosphorus-substituted dialkylamides of organophosphorus acids, containing PCH2NP fragments
Prishchenko,Livantsov,Novikova,Livantsova,Koval',Grigor'ev
, p. 1317 - 1320 (2007/10/03)
Reactions of [N-(trimethylsilyl)aminomethyl]phosphonates with organophosphorus acid chlorides was studied, which allowed to develop convenient synthetic approaches to novel phosphorus-substrituted dialkylamides of organophosphorus acids, including a PCH2NP fragment. Certain properties of the resulting compounds are presented. 2004 MAIK "Nauka/Interperiodica".
Methylene phosphonoalkylphosphinates, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism
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, (2008/06/13)
The present invention involves novel methylene phosphonoalkylphosphinic acids, pharmaceutical compositions containing such compounds, and methods for treating or preventing pathological conditions characterized by abnormal calcium and phosphate metabolism by administering such compounds to a human or lower animal.
