1498-42-6Relevant articles and documents
Nuretdinova,Nikonova
, (1975)
Synthesis and properties of 4-(dibromomethyl)benzenecarbaldehyde
Gazizov, Mukattis B.,Ivanova, Svetlana Yu.,Bagauva, Liliya R.,Khairullin, Rafail A.,Musin, Rashid Z.
supporting information, p. 210 - 212 (2015/12/31)
4-(Dibromomethyl)benzenecarbaldehyde was synthesized for the first time using a new method which also allowed the co-preparation of terephthalic aldehyde. The reaction of this aldehyde with primary amines resulted in the formation of imines, including those containing an additional acetal group, while the reaction with trialkyl orthoformates led to the formation of acetals. The latter compounds were transformed into 4-(dibromomethyl)-substituted benzenes containing a phosphorus functional group in the side chain via consecutive reactions with phosphorus trichloride and the esters of P(III) acids.
New approach to the synthesis of phosphorodichloridites, phosphorochloridites, and trialkyl phosphites
Majewski, Piotr
experimental part, p. 942 - 955 (2010/01/17)
Different trivalent organophosphorus esters such as phosphorodichloridites, phosphorochloridites, and mixed trialkyl phosphites have been easily synthesized in good yields using a HCl-catalyzed reaction of the corresponding chlorophosphine and alkoxytrimethylsilane by mutual exchange of the alkoxy and chlorine ligand pIIICl/ROSiR′3; exchange reaction). Chemoselectivity of the exchange reaction with primary and secondary alkoxytrimethylsilanes, as well as with alkoxytrimethylsilanes and thioalkoxytrimethylsilanes, respectively, has also been examined. It has been also found that the substitution reaction of chlorophosphines with secondary amine occurs more rapidly than the exchange reaction with ROSiR′ 3.
Selective synthesis of organophosphites
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Page 5-6, (2008/06/13)
Disclosed herein is a process for the selective synthesis of triorganophosphites intermediates, including chloridites and dichloridites, from PX3 (X=Cl, Br or I), alcoholos and triorganoamines where alcohol and triorganoamine are added either (a) separately and concurrently, or (b) alternating equimolar portions of amine and alcohol.
