18088-10-3

Basic information

• Product Name: 2-Pyridinecarboxylicacid,4,6-dimethyl-(9CI)
• Synonyms: 2-Pyridinecarboxylicacid,4,6-dimethyl-(9CI);4,6-Dimethyl-2-pyridinecarboxylic acid;2-PYRIDINECARBOXYLICACID4,6-DIMETHYL-
• CAS NO: 18088-10-3
• Molecular Formula: C₈H₉NO₂
• Molecular Weight: 151.17
• Product Categories: GLYCINESCAFFOLD;CARBOXYLICACID
• Mol File: 18088-10-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 301.6°C at 760 mmHg
• Flash Point: 136.2°C
• Appearance: /
• Density: 1.183g/cm³
• Vapor Pressure: 0.000463mmHg at 25°C
• Refractive Index: 1.553
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-Pyridinecarboxylicacid,4,6-dimethyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinecarboxylicacid,4,6-dimethyl-(9CI)(18088-10-3)
• EPA Substance Registry System: 2-Pyridinecarboxylicacid,4,6-dimethyl-(9CI)(18088-10-3)

Safety Data

• Hazardous Substances Data: 18088-10-3(Hazardous Substances Data)

Usage

General Description

2-Pyridinecarboxylic acid, 4,6-dimethyl-(9CI) is a chemical compound with the molecular formula C9H9NO2. It is also known as 4,6-dimethyl-2-pyridinecarboxylic acid. 2-Pyridinecarboxylicacid,4,6-dimethyl-(9CI) is a derivative of pyridine and carboxylic acid, and it contains two methyl groups on the 4th and 6th carbon atoms of the pyridine ring. It is commonly used in the pharmaceutical industry for the synthesis of various drugs and as a building block for organic synthesis. 2-Pyridinecarboxylicacid,4,6-dimethyl-(9CI) has potential applications in the field of medicine, chemistry, and material science, making it an important and versatile chemical reagent.

InChI:InChI=1/C8H9NO2/c1-5-3-6(2)9-7(4-5)8(10)11/h3-4H,1-2H3,(H,10,11)

Upstream product

• 108-75-8 2,4,6-trimethyl-pyridine 
• 7584-11-4 4,6-dimethylpyridine-2-carbonitrile 
• 108-47-4 2,4-lutidine 
• 1122-45-8 2,4-dimethylpyridine N-oxide 
• 18087-99-5 4,6-dimethyl-2-(hydroxymethyl)pyridine 
• 13287-63-3 2-(4,6-dimethylpyridin-2-yl)ethanol 
• 7370-23-2 2,4-dimethyl-6-styryl-pyridine 
• 5439-01-0 4,6-dimethylpyridine-2-carbaldehyde 

Downstream Products

• 5439-01-0 4,6-dimethylpyridine-2-carbaldehyde 
• 5407-87-4 2-Amino-4,6-dimethylpyridine 
• 72693-02-8 4,6-dimethylpicolinamide 
• 108-47-4 2,4-lutidine 
• 69971-38-6 Methyl-4,6-dimethyl-2-pyridincarboxylat 

Relevant articles and documents

Fe(PyTACN)-catalyzed cis-dihydroxylation of olefins with hydrogen peroxide

A family of iron complexes with general formula [Fe(II)( R,Y,XPyTACN)(CF3SO3)2], where R,Y,XPyTACN=1-[2′-(4-Y-6-X-pyridyl)methyl]-4,7-dialkyl-1,4, 7-triazacyclononane, X and Y refer to the groups at positions 4 and 6 of the pyridine, respectively, and R refers to the alkyl substitution at N-4 and N-7 of the triazacyclononane ring, are shown to be catalysts for efficient and selective alkene oxidation (epoxidation and cis-dihydroxylation) employing hydrogen peroxide as oxidant. Complex [Fe(II)(Me,Me,HPyTACN)(CF 3SO3)2] (7), was identified as the most efficient and selective cis-dihydroxylation catalyst among the family. The high activity of 7 allows the oxidation of alkenes to proceed rapidly (30 min) at room temperature and under conditions where the olefin is not used in large amounts but instead is the limiting reagent. In the presence of 3 mol% of 7, 2 equiv. of H2O2 as oxidant and 15 equiv. of water, in acetonitrile solution, alkenes are cis-dihydroxylated reaching yields that might be interesting for synthetic purposes. Competition experiments show that 7 exhibits preferential selectivity towards the oxidation of cis olefins over the trans analogues, and also affords better yields and high [syn-diol]/[epoxide] ratios when cis olefins are oxidized. For aliphatic substrates, reaction yields attained with the present system compare favourably with state of the art Fe-catalyzed cis-dihydroxylation systems, and it can be regarded as an attractive complement to the iron and manganese systems described recently and which show optimum activity against electron-deficient and aromatic olefins. Copyright