1843-16-9

Basic information

• Product Name: PHENYL-(4-PHENYL-THIAZOL-2-YL)-AMINE
• Synonyms: N,4-diphenyl-2-Thiazolamine;N,4-diphenyl-1,3-thiazol-2-amine
• CAS NO: 1843-16-9
• Molecular Formula: C₁₅H₁₂N₂S
• Molecular Weight: 252.33
• Mol File: 1843-16-9.mol
• Article Data: 35

Chemical Properties

• Appearance: /
• CAS DataBase Reference: PHENYL-(4-PHENYL-THIAZOL-2-YL)-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: PHENYL-(4-PHENYL-THIAZOL-2-YL)-AMINE(1843-16-9)
• EPA Substance Registry System: PHENYL-(4-PHENYL-THIAZOL-2-YL)-AMINE(1843-16-9)

Safety Data

• Hazardous Substances Data: 1843-16-9(Hazardous Substances Data)

Upstream product

• 3282-32-4 2-diazo-acetophenone 
• 103-85-5 monophenylthiourea 
• 38650-46-3 3,4-diphenyl-2-imino-4-thiazoline 
• 98-86-2 acetophenone 
• 142-04-1 aniline hydrochloride 
• 57516-16-2 2-bromo-4-phenyl-1,3-thiazole 
• 17687-63-7 1-chloro-3-methylbutan-2-one 
• 7647-01-0 hydrogenchloride 
• 7257-94-5 1-phenyl-2-(p-tolylsulfonyloxy)ethanone 
• 43009-16-1 phenyldithiocarbamic acid triethylamine salt 
• 70-11-1 α-bromoacetophenone 
• 536-74-3 phenylacetylene 
• 1226922-89-9 C₅H₅N*C₇H₇NS₂ 
• 51034-34-5 potassium aniline dithiocarbamate 

Downstream Products

• 2211-45-2 (1H-benzoimidazol-2-ylmethyl)-phenyl-(4-phenyl-thiazol-2-yl)-amine 
• 1649989-07-0 2-phenylamino-4-phenyl-5-(benzylideneamino)-1,3-thiazole 
• 1649989-05-8 2-phenylamino-4-phenyl-5-nitroso-1,3-thiazole 
• 1198108-44-9 2,2'-(N,N'-diphenylamino)-4,4'-diphenyl-5,5'-phenylidenebisthiazole 
• 1198108-45-0 C₃₇H₂₇ClN₄S₂ 
• 1198108-48-3 C₃₇H₂₇FN₄S₂ 
• 72545-24-5 N-(4-diethylamino-phenyl)-glycine phenyl-(4-phenyl-thiazol-2-yl)-amide 
• 72545-23-4 N-(4-dimethylamino-phenyl)-glycine phenyl-(4-phenyl-thiazol-2-yl)-amide 
• 72545-27-8 N,N-diphenyl-glycine phenyl-(4-phenyl-thiazol-2-yl)-amide 
• 72545-19-8 2-morpholin-4-yl-N-phenyl-N-(4-phenyl-thiazol-2-yl)-acetamide 
• 72545-28-9 N-phenyl-N-(4-phenyl-thiazol-2-yl)-2-piperazin-1-yl-acetamide 
• 72545-20-1 N-phenyl-N-(4-phenyl-thiazol-2-yl)-2-piperidin-1-yl-acetamide 
• 72545-26-7 N-pyrimidin-2-yl-glycine phenyl-(4-phenyl-thiazol-2-yl)-amide 
• 72545-25-6 N-pyridin-2-yl-glycine phenyl-(4-phenyl-thiazol-2-yl)-amide 

Relevant articles and documents

Microwave promoted synthesis of functionalized 2-aminothiazoles

Microwave irradiation promotes the rapid one-pot synthesis of 2-aminothiazoles fromed via the condensation of α-bromoketones with thiourea.

Novel synthesis of 2-Aminothiazoles via Fe(III)-Iodine-catalyzed Hantzsch-type condensation

A novel iron-iodine catalyzed one pot synthesis of 2-aminothiazoles from methyl aryl ketones and thiourea is demonstrated. This protocol can be considered as a catalyzed version of the classical Hantzsch aminothiazole synthesis as it enables the in situ generation of α-iodoketones in the reaction medium using catalytic amount of iodine leading to Hantzsch condensation with thiourea. The supply of iodine for multiple catalytic cycles is ensured by using catalytic amounts of iron as it enables iodide to iodine oxidation. The generality of this protocol is also well established in this manuscript by synthesizing a variety of 2-aminothiazoles from different ketones and thiourea.

Thiocyanation and 2-Amino-1,3-thiazole Formation in Water Using Recoverable and Reusable Glycosylated Resorcin[4]arene Cavitands

A family of three spatially directional resorcin[4]arene cavitand glycoconjugates (RCGs) have been applied as efficient recoverable and reusable inverse phase transfer catalysts for eco- A nd environmentally friendly thiocyanation and 2-amino-1,3-thiazole formation reactions in water. The results show that RCGs (1 mol %) were capable of hosting and catalyzing various water-insoluble bromo/thiocyanato substrates in water without the use of any co-organic solvents. The recoverability and reusability of RCG catalytic systems, that is, RCG1 and RCG3, were also examined upon a simple extraction of the desired products using DCM or ethyl acetate, followed by subjecting the recovered aqueous solution containing the RCG catalysts to the next reaction cycles.