185249-90-5Relevant articles and documents
Convenient syntheses of 3-aryl-3,4-dihydroisocoumarins
Limaye, Rohan A.,Joseph, Augustine R.,Natu, Arun D.,Paradkar, Madhusudan V.
, p. 191 - 194 (2015/06/02)
A convenient method for the synthesis of naturally occurring 3,4-dihydroisocoumarins by judicious use of Friedel-Craft acylation, regioselective formylation and oxidative cyclisation reactions is described. O-methylated analogues of montroumarin and thunb
Benzylic Manganese Halides, Sulfonates, and Phosphates: Preparation, Coupling Reactions, and Applications in Organic Synthesis
Kim, Seung-Hoi,Rieke, Reuben D.
, p. 2322 - 2330 (2007/10/03)
The use of highly active manganese, prepared by the Rieke method, for the direct preparation of benzylic manganese reagents was investigated. The oxidative addition of the highly active manganese (Mn*) to benzylic halides was easily completed under mild conditions. More importantly, benzylic manganese sulfonates and phosphates were prepared by direct oxidative addition of Mn* to the carbon-oxygen bonds of benzylic sulfonates and phosphates. The resulting benzylic manganese reagents were found to undergo cross-coupling reactions with a variety of electrophiles. The majority of these reactions were carried out in the absence of any transition metal catalyst under mild conditions. This approach also provided a facile synthetic route to the preparation of resorcinolic lipids.
Combretastatin Analogs via Hydration of Stilbene Derivatives
Mannila, Erkki,Talvitie, Antti
, p. 1037 - 1040 (2007/10/02)
Hydration of the double bond of some stilbene congeners of Picea abies bark by TiCl4.NaBH4 reagent is described.Five racemic 1,2-diphenylethanol derivatives (9-13), structurally related to (R)-(-)combretastatin , have been obtained and characterize