186415-77-0

Basic information

• Product Name: C₄₄H₆₀O₃
• Synonyms: C₄₄H₆₀O₃
• CAS NO: 186415-77-0
• Molecular Weight: 636.959
• Mol File: 186415-77-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₄₄H₆₀O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₄₄H₆₀O₃(186415-77-0)
• EPA Substance Registry System: C₄₄H₆₀O₃(186415-77-0)

Safety Data

• Hazardous Substances Data: 186415-77-0(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 187394-38-3 3,24-O-benzylidene soyasapogenol B 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 124862-79-9 soyasapogenol B 

Downstream Products

• 186415-73-6 ((3S,4S,4aR,6aR,6bS,8aR,9R,12aS,14aR,14bR)-3,9-Bis-benzyloxy-4,6a,6b,8a,11,11,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydro-picen-4-yl)-methanol 
• 186415-78-1 (3S,4S,4aR,6aR,6bS,8aR,9R,12aS,14aR,14bR)-9-Benzyloxy-4-benzyloxymethyl-4,6a,6b,8a,11,11,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydro-picen-3-ol 
• 195155-81-8 N-n-butyl-3β,22β-dibenzyloxyolean-12-ene-24-amide 
• 6822-47-5 sophoradiol 
• 862248-29-1 3β,22β-dibenzyloxyolean-12-ene 
• 187394-37-2 3β,22β-dibenzyloxy-24-methoxyolean-12-ene 
• 187394-40-7 22β,24-dibenzyloxy-3β-methoxyolean-12-ene 
• 186415-74-7 (3S,4R,4aR,6aR,6bS,8aR,9R,12aS,14aR,14bR)-3,9-Bis-benzyloxy-4,6a,6b,8a,11,11,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydro-picene-4-carbaldehyde 
• 187393-82-4 (3S,4R,4aR,6aR,6bS,8aR,9R,12aS,14aR,14bR)-3,9-Bis-benzyloxy-4,6a,6b,8a,11,11,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydro-picene-4-carboxylic acid 
• 187394-34-9 24-acetoxy-3β,22β-dibenzyloxyolean-12-ene 
• 186415-79-2 (4R,4aR,6aS,6bR,8aR,9S,12aR,12bR,14bS)-4-Benzyloxy-9-benzyloxymethyl-2,2,4a,6a,6b,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,12,12a,12b,13,14b-octadecahydro-picene 
• 187394-39-4 Acetic acid (3S,4S,4aR,6aR,6bS,8aR,9R,12aS,14aR,14bR)-9-benzyloxy-4-benzyloxymethyl-4,6a,6b,8a,11,11,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydro-picen-3-yl ester 

Relevant articles and documents

Preventive effects of soyasapogenol B derivatives on liver injury in a concanavalin A-induced hepatitis model

To shed light on the structure-activity relationship, various soyasapogenol B derivatives were synthesized and evaluated for preventive effects on liver injury in the concanavalin A (Con A)-induced hepatitis model in mice. Con A injection into mice induces some pathophysiology of human liver disease such as autoimmune or viral hepatitis. Two hydroxyl groups on the A ring of soyasapogenol B are required for amelioration of liver damage. Modification of the C-22 hydroxyl moiety with an acyloxy or alkyloxy group, or removal of the hydroxyl group, resulted in a greatly enhanced percentage of alleviation. Among the series of soyasapogenol B derivatives examined, six compounds exhibited preventive effects on liver damage.