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195155-81-8

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195155-81-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 195155-81-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,5,1,5 and 5 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 195155-81:
(8*1)+(7*9)+(6*5)+(5*1)+(4*5)+(3*5)+(2*8)+(1*1)=158
158 % 10 = 8
So 195155-81-8 is a valid CAS Registry Number.

195155-81-8Downstream Products

195155-81-8Relevant articles and documents

Preventive effects of soyasapogenol B derivatives on liver injury in a concanavalin A-induced hepatitis model

Sasaki, Kazue,Minowa, Nobuto,Kuzuhara, Hiroyuki,Nishiyama, Shoji

, p. 4900 - 4911 (2007/10/03)

To shed light on the structure-activity relationship, various soyasapogenol B derivatives were synthesized and evaluated for preventive effects on liver injury in the concanavalin A (Con A)-induced hepatitis model in mice. Con A injection into mice induces some pathophysiology of human liver disease such as autoimmune or viral hepatitis. Two hydroxyl groups on the A ring of soyasapogenol B are required for amelioration of liver damage. Modification of the C-22 hydroxyl moiety with an acyloxy or alkyloxy group, or removal of the hydroxyl group, resulted in a greatly enhanced percentage of alleviation. Among the series of soyasapogenol B derivatives examined, six compounds exhibited preventive effects on liver damage.

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