66107-33-3

Basic information

• Product Name: Methanesulfonic acid, trifluoro-, 3-methoxyphenyl ester
• CAS NO: 66107-33-3
• Molecular Formula: C8H7F3O4S
• Molecular Weight: 256.202
• Mol File: 66107-33-3.mol
• Article Data: 23

Chemical Properties

• CAS DataBase Reference: Methanesulfonic acid, trifluoro-, 3-methoxyphenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Methanesulfonic acid, trifluoro-, 3-methoxyphenyl ester(66107-33-3)
• EPA Substance Registry System: Methanesulfonic acid, trifluoro-, 3-methoxyphenyl ester(66107-33-3)

Safety Data

• Hazardous Substances Data: 66107-33-3(Hazardous Substances Data)

Upstream product

• 217813-03-1 3-methoxy-2-(trimethylsilyl)phenyl-trifluoromethanesulfonate 
• 10365-98-7 3-methoxyphenylboronic acid 
• 2926-30-9 sodium triflate 
• 150-19-6 O-methylresorcine 
• 358-23-6 trifluoromethylsulfonic anhydride 
• 1493-13-6 trifluorormethanesulfonic acid 

Downstream Products

• 2113-56-6 3-methoxybiphenyl 
• 13145-84-1 (3-methoxyphenyl)(diphenyl)phosphane 
• 7000-87-5 N,N-Diisopropyl-3-methoxyaniline 
• 132514-79-5 N,N-Diisopropyl-4-methoxyaniline 
• 51451-80-0 N-(3-methoxyphenyl)-p-nitroaniline 
• 536-90-3 m-Anisidine 
• 57568-45-3 1-methoxy-3-(2-methylpropyl)benzene 
• 1146970-90-2 C₁₆H₂₄N₂O₃ 
• 456-49-5 1-fluoro-3-methoxybenzene 
• 65442-22-0 (3-methoxyphenyl)phosphonic acid diethyl ester 
• 1443013-65-7 (S)-α-(m-anisyl)-δ-valerolactone 
• 150-19-6 O-methylresorcine 
• 1461737-14-3 (S)-3-(m-anisyl)cyclopentene 

Relevant articles and documents

Facile synthesis of diverse multisubstituted ortho-silylaryl triflates via CH borylation

Diverse multisubstituted ortho-silylaryl triflates were efficiently synthesized from simple ortho-silylaryl triflates via iridium-catalyzed regioselective CH borylation and subsequent deborylative functionalizations. An azidoaryne precursor synthesized by this method served as a useful bis-reactive platform molecule, thus demonstrating the utility of the method for preparing diverse aromatic compounds.

Base-promoted selective O-phosphorylation of aryl triflates with P(O)-H compounds

Compared to previous transition metal-catalyzed C-phosphorylation reactions for constructing C–P bonds, in the absence of transition metal catalysts and ligands, a direct O-phosphorylation of aryl triflates selectively occurred with P(O)-H compounds in the presence of a base via the construction of O–P bonds. This transformation proceeds under simple and mild conditions, and provides a new method for the preparation of valuable organophosphoryl compounds from readily available P(O)-H compounds and triflates.

Transition-Metal-Free C-C, C-O, and C-N Cross-Couplings Enabled by Light

Transition-metal-catalyzed cross-couplings to construct C-C, C-O, and C-N bonds have revolutionized chemical science. Despite great achievements, these metal catalysts also raise certain issues including their high cost, requirement of specialized ligands, sensitivity to air and moisture, and so-called "transition-metal-residue issue". Complementary strategy, which does not rely on the well-established oxidative addition, transmetalation, and reductive elimination mechanistic paradigm, would potentially eliminate all of these metal-related issues. Herein, we show that aryl triflates can be coupled with potassium aryl trifluoroborates, aliphatic alcohols, and nitriles without the assistance of metal catalysts empowered by photoenergy. Control experiments reveal that among all common aryl electrophiles only aryl triflates are competent in these couplings whereas aryl iodides and bromides cannot serve as the coupling partners. DFT calculation reveals that once converted to the aryl radical cation, aryl triflate would be more favorable to ipso substitution. Fluorescence spectroscopy and cyclic voltammetry investigations suggest that the interaction between excited acetone and aryl triflate is essential to these couplings. The results in this report are anticipated to provide new opportunities to perform cross-couplings.