188562-97-2

Upstream product

• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 
• 188562-93-8 4-[N-benzyl-N-(tert-butoxycarbonyl)amino]cyclohex-1-en-yl trifluoromethanesulfonate 
• 422506-83-0 4-[N-benzyl-N-(tert-butoxycarbonyl)amino]-1-iodocyclohex-1-ene 
• 131511-13-2 4-(N-benzylamino)cyclohexanone ethylene acetal 
• 100-46-9 benzylamine 
• 142009-99-2 4-(benzylamino)cyclohexane-1-one 
• 4746-97-8 cyclohexanedione monoethylene ketal 
• 188562-91-6 tert-butyl N-benzyl(4-oxocyclohexyl)carbamate 

Downstream Products

• 188562-99-4 methyl 4-benzylaminocyclohex-1-ene-1-carboxylate 
• 422506-89-6 methyl 4-[N-benzyl-N-(tert-butoxycarbonylmethyl)amino]cyclohex-1-enecarboxylate 
• 422506-97-6 methyl 4-{N-benzyl-[2-(phenylselanyl)-2-oxoethyl]amino}cyclohex-1-enecarboxylate 

Relevant academic research and scientific papers

Decarbonylative radical cyclization of α-amino selenoesters upon electrophilic alkenes. A general method for the 6-azabicyclo[3.2.1]octane synthesis

α-Amino selenoester-tethered electronically poor alkenes on treatment with tributyltin hydride or TTMSS undergo intramolecular radical cyclization to provide 6-azabicyclo[3.2.1]octanes through 1-aminomethyl radical intermediates.

Synthesis of 2-azabicyclo[3.3.1]lnonanes by means of (carbamoyl)dichloromethyl radical cyclization

A new procedure for the synthesis of 2-azabicyclo[3.3.1]nonanes by intramolecular carboradical cyclization of 4-(trichloroacetamido)cyclohexenes substituted with an electron withdrawing substituent tester or nitrile) is described. The procedure allows the preparation of synthetically interesting azabicyclos 14 and 15 in nearly 70% yield.