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191480-61-2

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191480-61-2 Usage

General Description

1S,2S-N,N'-bis(phenylMethyl)-1,2-CyclohexanediaMine is a chemical compound with the molecular formula C20H26N2. It is a chiral diamine with two phenylmethyl groups attached to a 1,2-cyclohexanediamine backbone. 1S,2S-N,N'-bis(phenylMethyl)-1,2-CyclohexanediaMine has been used as a chiral ligand in various asymmetric synthesis reactions. It has also been found to exhibit biological activity as an anti-inflammatory and anti-cancer agent. The compound has potential applications in organic synthesis, pharmaceuticals, and materials science due to its chiral nature and versatile reactivity. Safety and regulatory information should be consulted when handling and using 1S,2S-N,N'-bis(phenylMethyl)-1,2-CyclohexanediaMine.

Check Digit Verification of cas no

The CAS Registry Mumber 191480-61-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,1,4,8 and 0 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 191480-61:
(8*1)+(7*9)+(6*1)+(5*4)+(4*8)+(3*0)+(2*6)+(1*1)=142
142 % 10 = 2
So 191480-61-2 is a valid CAS Registry Number.

191480-61-2Relevant articles and documents

Machine-Assisted Preparation of a Chiral Diamine Ligand Library and In Silico Screening Using Ab Initio Structural Parameters for Heterogeneous Chiral Catalysts

Kobayashi, Shū,Kuremoto, Tatsuya,Sadatsune, Ren,Yamashita, Yasuhiro,Yasukawa, Tomohiro

supporting information, p. 4204 - 4208 (2021/08/09)

A ligand library containing 31 chiral diamines was synthesized using a flow-based semiautomatic reductive amination system. These ligands were evaluated in a continuous-flow asymmetric 1,4-addition reaction with a heterogeneous Ni catalyst. Based on the experimental results of ab initio DFT calculations, a prediction model for enantioselectivities was successfully constructed. Furthermore, virtual screening of possible ligands was conducted to identify promising structures, which showed good enantioselectivities in experiments. (Figure presented.).

METAL CHELATORS FOR IMAGING, THERAPEUTICS, AND BIOANALYSIS

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Paragraph 0160, (2018/09/26)

A variety of compounds are provided capable of chelating a metal, in particular a lanthanide such as Eu(III) and Tb(III). Luminescent complexes of the compound and a metal ion are also provided, in particular luminescent metal complexes are provided containing a lanthanide such as Eu(III) or Tb(III) and a compound described herein. In some aspects, the luminescent complexes are capable of exhibiting bright emissions with high quantum yields. Methods of making the compound are provided. Methods of using the compounds and luminescent complexes are also provided, for example for imaging and therapeutic applications.

Efficient route to pre-organized and linear polyaminopolycarboxylates: Cy-TTHA, Cy-DTPA and mono/di- reactive, tert-butyl protected TTHA/Cy-TTHA

Mohamadi, Ali,Miller, Lawrence W.

supporting information, p. 1441 - 1444 (2017/03/23)

Pre-organized polyaminopolycarboxylate chelators Cy-TTHA and Cy-DTPA were synthesized via modular five-step syntheses from commercially available starting materials in ~62% and 47% overall yields, respectively. Furthermore, strategies are reported for the efficient preparation of mono- and di-reactive, tert-butyl-protected TTHA/Cy-TTHA to selectively functionalize central chelators’ carboxylic acids.

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