19159-25-2

Usage

Uses

Used in Organic Chemistry:
Trimethylsilylsucrose is used as a silylating agent for silanization, which is a process that covers a material with a thin layer of silicone. This application is beneficial for protecting materials from moisture or chemical attacks and for reducing friction on the material's surface.
Used in Material Protection:
In the field of material science, trimethylsilylsucrose is used as a protective coating agent. The silanization process it facilitates helps safeguard materials from environmental factors such as moisture and chemical exposure, thereby enhancing their durability and lifespan.
Used in Friction Reduction:
Trimethylsilylsucrose is also utilized in applications where reducing friction is essential. By applying a thin silicone layer through the silanization process, it can decrease the coefficient of friction on materials, which is particularly useful in industrial and manufacturing settings where wear and tear are concerns.

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 57-50-1 Sucrose 
• 4648-54-8 trimethylsilylazide 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 13257-81-3 4-trimethylsiloxy-3-penten-2-one 

Downstream Products

• 69-65-8 mannitol 
• 50-70-4 D-sorbitol 
• 154-58-5 1,5-anhydro-D-glucitol 
• 27826-73-9 2,5-anhydro-D-glucitol 
• 1498304-83-8 6’-O-diphenoxyphosphoryl-2,3,4,6,1’,2’,3’-hexa-O-trimethylsilyl-α,α'-sucrose 
• 36064-19-4 sucrose 6’-monophosphate dipotassium salt 

Relevant academic research and scientific papers

Simple one-pot regioselective 6-O-phosphorylation of carbohydrates and trehalose desymmetrization

Biologically essential carbohydrate 6-phosphates, especially trehalose 6-phosphate, can be synthesized easily in excellent overall yields in 2 steps involving minimum protecting group manipulations. We can cleave the diphenylphosphate group for further synthetic objectives.

Regioselective azidotrimethylsilylation of carbohydrates and applications thereof

Azidotrimethylsilylation of carbohydrates (monosaccharides and disaccharides) has been achieved in high yields under Mitsunobu conditions. The azidation of carbohydrates is effected at 0 °C essentially only at the primary alcoholic position in mono, di- and triols in protected/unprotected glycosides, whereas the remaining secondary hydroxyl groups got silylated. Surprisingly, no azidation of the secondary hydroxyls was observed in all the carbohydrate substrates. Applications of the methodology for the synthesis of amino sugars, triazoles and azasugars are reported.

Highly atom economical uncatalysed and I2-catalysed silylation of phenols, alcohols and carbohydrates, using HMDS under solvent-free reaction conditions (SFRC)

An uncatalysed silylation of phenols, regardless on the aggregate state and nature of the substituents with 0.55 equiv of HMDS under solvent-free reaction conditions (SFRC) at room temperature is reported. Sterically hindered phenols, carbohydrates and most of the alcohols additionally required a catalytic amount (up to 2 mol %) of iodine. The reaction protocol is very simple; obtaining a pure product, particularly of uncatalysed reactions, was frequently a completely solvent-free process.