TRIMETHYLSILYLSUCROSE

Base Information

• Chemical Name: TRIMETHYLSILYLSUCROSE
• CAS No.: 19159-25-2
• Molecular Formula: C36H86 O11 Si8
• Molecular Weight: 919.756
• Mol file: 19159-25-2.mol

Synonyms:Glucopyranoside,1,3,4,6-tetrakis-O-(trimethylsilyl)-b-D-fructofuranosyl2,3,4,6-tetrakis-O-(trimethylsilyl)- (7CI); Sucrose,octakis-O-(trimethylsilyl)- (6CI); Octa-O-(trimethylsilyl)sucrose

Chemical Property of TRIMETHYLSILYLSUCROSE

Chemical Property:

• PSA: 101.53000
• LogP: 9.47800
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of TRIMETHYLSILYLSUCROSE

There total 5 articles about TRIMETHYLSILYLSUCROSE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

1,1,1,3,3,3-hexamethyl-disilazane (999-97-3) + Sucrose (57-50-1) → sucrose octakis(trimethylsilyl) ether (19159-25-2)

Guidance literature:

With iodine; at 20 ℃; Neat (no solvent); Air atmosphere;

DOI:10.1016/j.tet.2012.03.040

Reference yield: 58.0%

trimethylsilylazide (4648-54-8) + Sucrose (57-50-1) → 6,6′-di-azido-6,6′-di-deoxy-2,3,4,1′,3′,4′-hexa-O-trimethylsilylsucrose (1414630-00-4) + sucrose octakis(trimethylsilyl) ether (19159-25-2)

Guidance literature:

Sucrose; With di-isopropyl azodicarboxylate; triphenylphosphine; In toluene; at 0 ℃; for 0.5h; Inert atmosphere;

trimethylsilylazide; In toluene; at 0 ℃; for 3h; regioselective reaction; Inert atmosphere;

DOI:10.1039/c2ob26324f

Reference yield:

chloro-trimethyl-silane (75-77-4) + Sucrose (57-50-1) → sucrose octakis(trimethylsilyl) ether (19159-25-2)

Guidance literature:

With pyridine; hexane; formamide;

DOI:10.1002/macp.1957.020240101

upstream raw materials:

chloro-trimethyl-silane

Sucrose

4-trimethylsiloxy-3-penten-2-one

1,1,1,3,3,3-hexamethyl-disilazane

Downstream raw materials:

D-sorbitol

1,5-anhydro-D-glucitol

2,5-anhydro-D-glucitol

mannitol

Refernces

• 1、 Chang,Hass. "-". . p. 773. Retrieved 1958.
• 2、 Jereb, Marjan. "Highly atom economical uncatalysed and I2-catalysed silylation of phenols, alcohols and carbohydrates, using HMDS under solvent-free reaction conditions (SFRC)". experimental part. p. 3861 - 3867. Retrieved 2012/06/30.
• 3、 Taba, Kalulu M.,Dahlhoff, Wilhelm Volker. "Boron Compounds; LV. A New O-Silylation Method via Diethylboryl Ethers and Esters". . p. 652 - 653. Retrieved 2007/10/02.