19319-32-5

Basic information

• Product Name: 3-(4-methoxyphenyl)-2-phenylacrylic acid
• Synonyms: 3-(4-methoxyphenyl)-2-phenylacrylic acid;(2Z)-3-(4-METHOXYPHENYL)-2-PHENYLACRYLIC ACID;(2Z)-3-(4-methoxyphenyl)-2-phenylacrylic acid(SALTDATA: FREE);(Z)-3-(4-methoxyphenyl)-2-phenyl-acrylic acid;(Z)-3-(4-methoxyphenyl)-2-phenyl-prop-2-enoic acid;(Z)-3-(4-methoxyphenyl)-2-phenylprop-2-enoic acid;3-(4-methoxyphenyl)-2-phenyl-prop-2-enoic acid;3-(4-methoxyphenyl)-2-phenylprop-2-enoic acid
• CAS NO: 19319-32-5
• Molecular Formula: C₁₆H₁₄O₃
• Molecular Weight: 254.29
• Mol File: 19319-32-5.mol
• Article Data: 21

Chemical Properties

• Boiling Point: 386.9°C at 760 mmHg
• Flash Point: 141.7°C
• Appearance: /
• Density: 1.204g/cm³
• Vapor Pressure: 1.11E-06mmHg at 25°C
• Refractive Index: 1.63
• CAS DataBase Reference: 3-(4-methoxyphenyl)-2-phenylacrylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-methoxyphenyl)-2-phenylacrylic acid(19319-32-5)
• EPA Substance Registry System: 3-(4-methoxyphenyl)-2-phenylacrylic acid(19319-32-5)

Safety Data

• Hazardous Substances Data: 19319-32-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C16H14O3/c1-19-14-9-7-12(8-10-14)11-15(16(17)18)13-5-3-2-4-6-13/h2-11H,1H3,(H,17,18)/b15-11-

Upstream product

• 591-50-4 iodobenzene 
• 6968-77-0 3-(4-methoxyphenyl)-2-phenylacrylic acid 
• 879008-22-7 3c-(4-hydroxy-phenyl)-2-phenyl-acrylic acid 
• 77-78-1 dimethyl sulfate 
• 123-11-5 4-methoxy-benzaldehyde 
• 132274-45-4 2-(4-Methoxyphenyl)-2-(trimethylsilyl)-1,3-dithiane 
• 75748-09-3 (4-methoxybenzoyl)trimethylsilane 
• 24588-72-5 2-(4-methoxyphenyl)-1,3-dithiane 
• 13938-22-2 (E)-4-(4-methoxyphenyl)-3-phenylbut-3-en-2-one 
• 101-41-7 benzeneacetic acid methyl ester 
• 123-08-0 4-hydroxy-benzaldehyde 
• 103-82-2 phenylacetic acid 
• 13033-52-8 isopropyl-[1-(4-methoxyphenyl)meth-(E)-ylidene]amine 
• 23074-46-6 (p-Methoxyphenyl)-phenylcyclopropenon 

Downstream Products

• 34904-89-7 2-acetoxy-2-(4-methoxyphenyl)-1-phenylethanone 
• 22711-21-3 4-methoxybenzil 
• 1657-53-0 cis-4-methoxystilbene 
• 106319-23-7 (2R)-3-(4-methoxyphenyl)-2-phenylpropanoic acid 
• 70250-09-8 4-Methoxy-α-phenyl-trans-zimtsaeurechlorid 
• 1261237-39-1 (E)-N-ethyl-3-(4-methoxyphenyl)-2-(phenyl)-prop-2-enamide 
• 1261237-37-9 (E)-N-methyl-3-(4-methoxyphenyl)-2-(phenyl)-prop-2-enamide 
• 7605-44-9 (E)-methyl 3-(4-methoxyphenyl)-2-(phenyl)-prop-2-enoate 
• 109250-59-1 ethyl 3-(4-methoxyphenyl)-2-phenylpropanoate 
• 38828-28-3 (+/-)-threo-α'-benzoyloxy-4'-methoxy-bibenzyl-α-ol 
• 38828-28-3 (+/-)-erythro-α'-benzoyloxy-4'-methoxy-bibenzyl-α-ol 
• 66749-56-2 (1RS:2RS)-2-phenyl-1-(4-methoxy-phenyl)-ethanediol-(1,2) 
• 108840-75-1 6-methoxy-2-phenylindan-1-one 
• 13938-23-3 1-acetoxy-4t-(4-methoxy-phenyl)-3-phenyl-but-3-en-2-one 

Relevant articles and documents

Antioxidant, anti-tyrosinase and anti-melanogenic effects of (E)-2,3-diphenylacrylic acid derivatives

During our continued search for strong skin whitening agents over the past ten years, we have investigated the efficacies of many tyrosinase inhibitors containing a common (E)-β-phenyl-α,β-unsaturated carbonyl scaffold, which we found to be essential for

Surface enhanced Raman spectroscopic (SERS) behavior of substituted propenoic acids used in heterogeneous catalytic asymmetric hydrogenation

The strength and geometry of adsorption of substituted propenoic acids on silver surface were studied by means of surface enhanced Raman spectroscopy (SERS) using silver sol. Based on their SERS behavior, two classes of phenylpropenoic acids studied were distinguished. The first class of propenoic acids (atropic acid, (E)-2,3-diphenylpropenoic acid, (E)-2-(2-methoxyphenyl)-3-phenylpropenoic acid, (E)-2,3-di-(4-methoxyphenyl)phenylpropenoic acid and (E)-2-(2-methoxyphenyl)-3-(4-fluorophenyl)propenoic acid) has shown strong charge transfer (CT) effect. We suggest bidentate carboxyl bonded species based on the SERS enhanced bands of νCOO- around 1394 cm-1 and νC-C of the -C-COO- moiety at 951 cm-1. In these series the plane of the α-phenyl group (γCH out-of-plane vibrations at 850-700 cm-1) is almost parallel to the silver surface, while the β-phenyl group is in tilted position depending on the type and the position of substituent(s) showing strong SERS enhanced bands of νCC + βCH (in-plane mode) at 1075 cm-1, νCC (ring breathing mode, in-plane) at 1000 cm-1 and γCCC (out-of-plane mode) around 401 cm-1. The other class of propenoic acids (cinnamic acid, (E)-2-phenyl-3-(4-methoxyphenyl)propenoic acid) has shown weak electromagnetic (EM) enhancement (CC bands is enhanced in cinnamic acid). In this case no significant carboxyl enhancement was observed, so we suggest that adsorbed species lie parallel to the surface. The two types of adsorption can be related to the dissociation ability of the carboxylic group. In the first case the carboxylic H dissociates, while in the second case it does not, as indicated also by the characteristic νCO band at 1686 cm-1 in the FT-Raman spectra of methanolic solutions.

Synthesis and biological evaluation of some stilbene derivatives

Several trans and cis stilbenes with substitution n the olefinic bridge were synthesized and characterized by IR, NMR and mass spectroscopy in an effort to obtain ubstances that could be more readily formulated. All the synthesized compounds were screened against Molt4/C8, CEM and L1210 cell lines. None of these compounds were ndowed with pronounced cytostatic activity. However,Schiff derivatives emerged as cytostatic agents (IC50: 0.77-10 μg/ml) that deserve further investigation. Springer Science+Business Media, LLC 2010.