195381-16-9

Usage

Structure

A five-membered aromatic ring containing four carbon atoms and one nitrogen atom, with two phenyl groups attached to the second carbon of the pyrrole ring.

Type

A derivative of pyrrole.

Usage

Commonly used in organic synthesis and pharmaceutical research due to its potential biological activity and structural versatility.

Potential application

Studied for its potential application in the development of new materials and as a molecular building block in supramolecular chemistry.

Upstream product

• 109-97-7 pyrrole 
• 100-52-7 benzaldehyde 
• 123-11-5 4-methoxy-benzaldehyde 
• 179811-42-8 2,5-bis(1-phenyl-1-hydroxymethyl)thiophenepyrrole 
• 98-86-2 acetophenone 
• 611-73-4 Benzoylformic acid 
• 352438-53-0 phenyl(5-benzoylpyrrol-2-yl)pyrrol-2-ylmethane 
• 107798-98-1 5-phenyldipyrromethane 
• 10002-30-9 S-pyridin-2-yl benzenecarbothioate 
• 352423-56-4 C₂₂H₂₀N₂O 
• 13707-46-5 N-tosyl-4-nitrobenzaldimine 
• 1137951-09-7 4-methyl-N-(phenyl(5-(phenyl(1H-pyrrol-2-yl)methyl)-1H-pyrrol-2-yl)methyl) benzene sulfonamide 
• 555-16-8 4-nitrobenzaldehdye 
• 51608-60-7 N-(benzylidene)-p-methylbenzenesulfonamide 

Downstream Products

• 1392132-09-0 methoxy(5,10-diphenyl-15-(4-methoxyphenyl)ethynylsubporphyrinato)boron(III) 
• 1392132-10-3 methoxy(5,10-diphenyl-15-(4-nitrophenyl)ethynylsubporphyrinato)boron(III) 
• 1392132-11-4 methoxy(5-(4-(N,N-dimethylamino)phenyl)ethynyl-10,15-diphenylsubporphyrinato)boron(III) 
• 1392132-12-5 methoxy(5-(4-(N,N-dibenzylamino)phenyl)ethynyl-10,15-diphenylsubporphyrinato)boron(III) 
• 1392132-14-7 methoxy(5,10-diphenyl-15-trimethylsilylethynylsubporphyrinato)boron(III) 
• 1392132-15-8 C₆₀H₃₈B₂N₆O₂ 
• 1392132-03-4 methoxo(5,10-diphenylsubporphyrinato)boron(III) 
• 1392132-04-5 methoxo(5-bromo-10,15-diphenylsubporphyrinato)boron(III) 
• 1392132-05-6 methoxy(5-benzyl-10,15-diphenylsubporphyrinato)boron(III) 
• 1392132-06-7 methoxy(5,10-diphenyl-15-(methyl pentanoate)subporphyrinato)boron(III) 

Relevant academic research and scientific papers

Tuning the thermodynamic onset potential of electrocatalytic O2 reduction reaction by synthetic iron-porphyrin complexes

A porphyrin ligand with two β-pyrrolic electron withdrawing ester groups is synthesized and its Co complex is crystallographically characterized. The iron complex of this porphyrin ligand shows an ～200 mV positive shift in its FeIII/II potential in organic as well as aqueous solvents and in the onset potential of ORR relative to that of an unsubstituted porphyrin.

K2S2O8mediated synthesis of 5-Aryldipyrromethanes and meso-substituted A4-Tetraarylporphyrins

The synthesis of dipyrromethanes from pyrrole and arylglyoxylic acids in the presence of K2S2O8at 90 C is reported affording dipyrromethanes in very good yields. Unlike an excess pyrrole traditionally used in dipyrromethane synthesis, the current method uses a stoichiometric amount of pyrrole avoiding any use of Br?nsted or Lewis acid. A gram scale synthesis of 5-phenyldipyrromethane is also achieved demonstrating potential scale up of dipyrromethanes using this method feasible. Subsequently, dipyrromethanes were converted to A4tetraarylporphyrins also in the presence of K2S2O8at 90C. A direct synthesis of A4-tetraphenylporphyrin from excess pyrrole and phenylglyoxylic acid in the presence of K2S2O8 at 90C is also reported.

Selective Synthesis of Tripyrranes, Tetrapyrranes, and Corroles

A new, catalytic, and general methodology was developed for the direct synthesis of unsymmetrical AB-type tripyrranes by reaction of dipyrromethanesulfonamides with pyrrole. Key structure dipyrromethanesulfonamides were synthesized by the addition of meso

Pentaphyrins useful in the biomedical field

The present disclosure relates to novel pentaphyrins, which can be used for instance in the biomedical field, or in cation or anion binding applications or for manufacturing near infrared materials.

Effective meso fabrications of subporphyrins

A meso-free subporphyrin was prepared and quantitatively converted into meso-brominated subporphyrin, which is an effective precursor for the facile installation of substituents at the meso position. The meso-(4-amino) phenylethynyl subporphyrins (see picture; N blue, O red, Br orange, F pale green, B dark green) and a butadiyne-bridged dimer have split Soret-like bands and red-shifted and intensified fluorescence. Copyright

Tetrathiafulvalene porphyrins

Four tetrathiafulvalene (TTF)-annulated porphyrins 1-4 were synthesized and characterized. All contain a tetraphenylporphyrin (TPP) core onto which four, two, or one TTF subunits were annulated. Absorption and fluorescence spectroscopic studies together w

Organocatalytic synthesis of dipyrromethanes by the addition of N-methylpyrrole to aldehydes

The reaction of aldehydes with N-methylpyrrole carried out in the presence of catalytic pyrrolidinium tetrafluoroborate at room temperature affords the corresponding dipyrromethanes and minor amounts of tripyrranes. This new, mild, and convenient process

New polyethyleneglycol-functionalized texaphyrins: Synthesis and in vitro biological studies

The synthesis of four new analogues of motexafin gadolinium (MGd), a gadolinium(iii) texaphyrin complex in clinical trials for its anticancer properties, is described. These new derivatives contain either 1,2-diaminobenzene or 2,3-diaminonaphthalene subun

Efficient synthesis of meso-substituted corroles in a H2O-MeOH mixture

New and efficient conditions for the synthesis of meso-substituted corroles were developed. The first step, involving the reaction of aldehydes with pyrrole, was carried out in a water-methanol mixture in the presence of HCl. A relatively narrow distribut

Scalable synthesis of dipyrromethanes

A (preferably nonaqueous) method of making a dipyrromethane is described. The comprises the steps of: (a) providing a reaction system consisting essentially of an aldehyde or acetal, excess pyrrole and a catalyst; (b) reacting the aldehyde or acetal with the pyrrole in the reaction system to form the dipyrromethane therein; (c) quenching the reaction system by adding a base thereto (preferably without simultaneously or concurrently adding water and/or an organic solvent thereto); (d) separating the catalyst from the reaction system; and then (e) separating the pyrrole from the reaction system to produce the dipyrromethane as a residual