19756-72-0

Basic information

• Product Name: TERT-BUTYL 4-NITROBENZOATE
• Synonyms: BUTTPARK 18\02-56;TERT-BUTYL 4-NITROBENZOATE
• CAS NO: 19756-72-0
• Molecular Formula: C₁₁H₁₃NO₄
• Molecular Weight: 223.23
• Mol File: 19756-72-0.mol
• Article Data: 36

Chemical Properties

• Boiling Point: 328.1°Cat760mmHg
• Flash Point: 139.5°C
• Appearance: /
• Density: 1.182g/cm³
• Vapor Pressure: 0.000194mmHg at 25°C
• Refractive Index: 1.531
• CAS DataBase Reference: TERT-BUTYL 4-NITROBENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: TERT-BUTYL 4-NITROBENZOATE(19756-72-0)
• EPA Substance Registry System: TERT-BUTYL 4-NITROBENZOATE(19756-72-0)

Safety Data

• Hazardous Substances Data: 19756-72-0(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 77, p. 6214, 1955 DOI: 10.1021/ja01628a045

InChI:InChI=1/C11H13NO4/c1-11(2,3)16-10(13)8-4-6-9(7-5-8)12(14)15/h4-7H,1-3H3

Upstream product

• 122-04-3 4-nitro-benzoyl chloride 
• 75-65-0 tert-butyl alcohol 
• 115-11-7 isobutene 
• 62-23-7 4-nitro-benzoic acid 
• 865-47-4 potassium tert-butylate 
• 619-50-1 4-nitrobenzoic acid methyl ester 
• 3847-57-2 sodium 4-nitrobenzoate 
• 636-97-5 N-amino-(4-nitrophenyl)carboxamide 
• 774-65-2 benzoic acid tert-butyl ester 
• 7697-37-2 nitric acid 
• 75-91-2 tert.-butylhydroperoxide 
• 555-16-8 4-nitrobenzaldehdye 
• 619-73-8 4-nitrobenzyl chloride 
• 83766-88-5 2-tert-butoxypyridine 

Downstream Products

• 18144-47-3 tert-butyl 4-aminobenzoate 
• 354116-63-5 4-hydroxyamino-benzoic acid tert-butyl ester 
• 62-23-7 4-nitro-benzoic acid 
• 115-11-7 isobutene 
• 1234-27-1 4,4'-(carbonylbis(azanediyl))dibenzoic acid 
• 1070977-95-5 1,3-bis(4-(3-(4-(pyrrolidin-1-yl)butanamido)phenylcarbamoyl)phenyl)urea 
• 1070977-87-5 1,3-bis(4-(4-(4-(pyrrolidin-1-yl)butanamido)phenylcarbamoyl)phenyl)urea 
• 1070977-85-3 1,3-bis(4-(4-(3-(pyrrolidin-1-yl)propanamido)phenylcarbamoyl)phenyl)urea 
• 1070977-92-2 1,3-bis(4-(3-(3-(pyrrolidin-1-yl)propanamido)phenylcarbamoyl)phenyl)urea 
• 1070977-90-0 1,3-bis(4-(3-(2-(pyrrolidin-1-yl)acetamido)phenylcarbamoyl)phenyl)urea 
• 1070977-83-1 1,3-bis(4-(4-(2-(pyrrolidin-1-yl)acetamido)phenylcarbamoyl)phenyl)urea 
• 1070978-92-5 4,4'-ureylene-di-(tert-butylbenzoate) 
• 122-04-3 4-nitro-benzoyl chloride 
• 1369962-92-4 tert-butyl 4-{[4-hydroxy-1-oxo-1-(prop-2-en-1-yloxy)butan-2-yl](methylsulfonyl)amino}benzoate 

Relevant articles and documents

Nickel-Catalyzed Esterification of Amides Under Mild Conditions

Abstract: The use of ligands to adjust the catalytic activity of the catalyst for esterification of amides is challenge in organic chemistry. In this paper, Nickel(II)-NHC-catalyzed the esterification reaction between N,N-di-Boc amide and alcohols at room temperature have been demonstrated. The imidazolium salt bearing a hydroxyl functionalized side arm showed high effective catalytic activity in the activation of the amide N–C bond in air atmosphere. Graphic Abstract: [Figure not available: see fulltext.].

Mild alkaline hydrolysis of hindered esters in non-aqueous solution

Sterically hindered esters of carboxylic acids, which are considered very resistant to saponification, were rapidly and efficiently saponified in a non-aqueous medium using NaOH in MeOH/CH2Cl2 (1:9) at room temperature. Furthermore, this reaction protocol was extended and successfully applied to the hydrolysis of tosylates and N-tosyl indoles.