1978-59-2

Basic information

• Product Name: 4-(4-Halophenyl)-1,2,3,6-terahydropyridinehydrochloride
• Synonyms: 4-(4-Halophenyl)-1,2,3,6-terahydropyridinehydrochloride;4-FLUOROPHENYL-1,2,3,6-TETRAHYDROPYRIDINE;Pyridine, 4-(4-fluorophenyl)-1,2,3,6-tetrahydro-
• CAS NO: 1978-59-2
• Molecular Formula: C₁₁H₁₂FN
• Molecular Weight: 177.22
• Mol File: 1978-59-2.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 264°Cat760mmHg
• Flash Point: 113.4°C
• Appearance: /
• Density: 1.092g/cm³
• Vapor Pressure: 0.00997mmHg at 25°C
• Refractive Index: 1.534
• PKA: 9.34±0.10(Predicted)
• CAS DataBase Reference: 4-(4-Halophenyl)-1,2,3,6-terahydropyridinehydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-Halophenyl)-1,2,3,6-terahydropyridinehydrochloride(1978-59-2)
• EPA Substance Registry System: 4-(4-Halophenyl)-1,2,3,6-terahydropyridinehydrochloride(1978-59-2)

Safety Data

• Hazardous Substances Data: 1978-59-2(Hazardous Substances Data)

Usage

General Description

4-(4-Halophenyl)-1,2,3,6-tetrahydropyridine hydrochloride is a chemical compound with potential use in pharmaceuticals and medicinal research. It is a derivative of tetrahydropyridine, a class of organic compounds with a six-membered ring containing one nitrogen atom. The 4-(4-Halophenyl) substitution on the pyridine ring confers specific properties and potential biological activity. The presence of the hydrochloride salt form in the compound indicates that it is suitable for use in aqueous solutions and pharmaceutical formulations. Further research and development of this chemical could lead to the discovery of new drugs for various medical conditions.

InChI:InChI=1/C11H12FN/c12-11-3-1-9(2-4-11)10-5-7-13-8-6-10/h1-5,13H,6-8H2

Upstream product

• 350-40-3 2-(4-fluorophenyl)-1-propene 
• 163630-90-8 4-(4-Fluoro-phenyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid 2,2,2-trichloro-ethyl ester 
• 1765-93-1 4-fluoroboronic acid 
• 375853-82-0 tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-1(2H)-pyridinecarboxylate 
• 352-34-1 4-fluoro-1-iodobenzene 
• 1978-61-6 4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridine hydrochloride 
• 460-00-4 1-Bromo-4-fluorobenzene 
• 163630-89-5 4-(4-fluorophenyl)-1,2,3,6-tetrahydro-1-(phenylmethyl)pyridine 
• 163631-02-5 1-benzyl-4-(4-fluorophenyl)-4-hydroxypiperidine 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 352-13-6 4-flourophenylmagnesium bromide 
• 553631-05-3 tert-butyl 4-hydroxy-4-(4-fluorophenyl)-1-piperidinecarboxylate 
• 138647-49-1 4-Trifluoromethanesulfonyloxy-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 
• 138647-52-6 4-(4-fluorophenyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 508239-30-3 5-(2-Ethoxyethylamino)-8-[4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridin-1-ylmethyl]-2-(2-furyl)[1,2,4]triazolo[1,5-c]pyrimidine 
• 748183-39-3 6-(4-fluorophenyl)-3-azabicyclo[4.1.0]heptane 
• 1007107-65-4 2-[4-(4-fluoro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinoline-3-carbonitrile 
• 1007107-55-2 C₂₂H₂₂BrFN₂O 
• 152565-98-5 C₂₀H₂₀FNO 

Relevant articles and documents

FLUORINE-CONTAINING COMPOUND AND ANTI-CANCER MEDICAL USE THEREOF

The present invention provides a fluorine-containing compound shown in Formula II/III and its anti-cancer medical use.

VMAT INHIBITORY COMPOUNDS

Disclosed herein are compounds that bind to the vesicular monoamine transporter 2 (VMAT2), pharmaceutical compositions comprising those compounds, and methods of treatment using said compounds and pharmaceutical compositions.

METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES

Methods, compounds, pharmaceutical compositions and kits are described for treating or preventing amyloid-related disease.