20002-32-8

Basic information

• Product Name: 1,2-diphenyl-1,2-di(o-tolyl)ethane-1,2-diol
• Synonyms: 1,2-diphenyl-1,2-di(o-tolyl)ethane-1,2-diol;1,2-Bis(2-methylphenyl)-1,2-diphenyl-1,2-ethanediol;1,2-Diphenyl-1,2-bis(2-methylphenyl)ethylene glycol;Einecs 243-458-9
• CAS NO: 20002-32-8
• Molecular Formula: C₂₈H₂₆O₂
• Molecular Weight: 394.50484
• EINECS: 243-458-9
• Mol File: 20002-32-8.mol

Chemical Properties

• Boiling Point: 529°Cat760mmHg
• Flash Point: 229.7°C
• Appearance: /
• Density: 1.165g/cm³
• Vapor Pressure: 5.07E-12mmHg at 25°C
• Refractive Index: 1.633
• CAS DataBase Reference: 1,2-diphenyl-1,2-di(o-tolyl)ethane-1,2-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-diphenyl-1,2-di(o-tolyl)ethane-1,2-diol(20002-32-8)
• EPA Substance Registry System: 1,2-diphenyl-1,2-di(o-tolyl)ethane-1,2-diol(20002-32-8)

Safety Data

• Hazardous Substances Data: 20002-32-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1,2-Diphenyl-1,2-di(o-tolyl)ethane-1,2-diol serves as an intermediate in the production of pharmaceuticals, contributing to the synthesis of various medicinal compounds. Its role in this industry is pivotal for creating new drugs and enhancing existing ones.
Used in Agrochemical Industry:
Similarly, in the agrochemical sector, di-o-tolylethane diol is employed as an intermediate for the synthesis of agrochemicals, which are essential for crop protection and enhancement of agricultural productivity.
Used in Polymer Science:
1,2-Diphenyl-1,2-di(o-tolyl)ethane-1,2-diol has been studied for its potential application in radical polymerization processes. It is used as a component in the development of new polymeric materials, which could have various applications across different industries due to their unique properties.

InChI:InChI=1/C28H26O2/c1-21-13-9-11-19-25(21)27(29,23-15-5-3-6-16-23)28(30,24-17-7-4-8-18-24)26-20-12-10-14-22(26)2/h3-20,29-30H,1-2H3

Upstream product

• 131-58-8 2-Methylbenzophenone 
• 75-16-1 methylmagnesium bromide 
• 677-22-5 tert-butylmagnesium chloride 
• 108-88-3 toluene 
• 98-88-4 benzoyl chloride 
• 71-43-2 benzene 
• 933-88-0 ortho-toluoyl chloride 
• 64-17-5 ethanol 
• 64-19-7 acetic acid 
• 60-29-7 diethyl ether 
• 100-58-3 phenylmagnesium bromide 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 87-24-1 ethyl 2-methylbenzoate 

Downstream Products

• 5472-13-9 2-methylbenzhydrol 
• 131-58-8 2-Methylbenzophenone 
• 120309-24-2 2,2-diphenyl-1,2-di-o-tolyl-ethanone 

Relevant articles and documents

NEW METHODOLOGY IN DETERMINING EVIDENCE FOR SINGLE ELECTRON TRANSFER IN THE REACTION OF GRIGNARD REAGENTS WITH KETONES

A new method is reported to determine the existence of single electron transfer in the reaction of Grignard reagents with ketones.The method involves the determination of pseudo-first order rate constants by following the rate of disappearance of the paramagnetic intermediate and relating the rate of this disappearance to the appearance of the product.The reactions of methyl-, phenyl- and t-butyl-Grignard reagents with substituted benzophenones were examined.This method should be applicable to a wide range of organometallic reactions.

ELECTRO-ORGANIC REACTIONS. PART 25. THE ROLE OF CHROMIUM(III) IN THE MODIFICATION OF CATHODIC PINACOLISATION

The presence of chromium(III) chloride, both hydrated and anhydrous, profoundly alters the course of cathodic in dimethylformamide solutions of benzophenone, benzaldehyde, β-ionone, β-ionylidene acetaldehyde, and retinal.Pinacolisation is enhanced at the expense of formation of the corresponding alcohol.Furthermore the relevant reduction potential is lowered.The mechanism of the reaction has been investigated using voltammetric and coulometric experiments combined with a detailed analysis of preparative-scale reductions under a variety of conditions.The stereochemical course of the reactions has also been considered.In total the results provide compelling evidence in favour of the key reducible intermediate being a carbonyl compound-Cr(III) complex which is formed via the corresponding Cr(III) species with homogenous, inner sphere, re-oxidation playing a crucial role.This is contrary to earlier suggestions invoking the participation of electrogenerated Cr(II) as the reductant.

Organometallic Reaction Mechanisms. 17. Nature of Alkyl Transfer in Reactions of Grignard Reagents with Ketones. Evidence for Radical Intermediates in the Formation of 1,2-Addition Product Involving Tertiary and Primary Grignard Reagents

When a Grignard reagent reacts with an aromatic ketone, a radical anion-radical cation pair is formed which can collapse to give 1,2-addition product or dissociate to form a radical anion and a free radical within the solvent cage which in turn can collapse to 1,2-addition product or a conjugate addition product or escape the solvent cage to form pinacol.The 1,2-addition products, which form after dissociation of the radical anion-radical cation pair, show free-radical character as indicated by the cyclized 1,2-addition products formed from the reaction of a tertiary Grignard reagent probe with benzophenone in THF and from the reaction of a primary Grignard reagent probe (neooctenyl Grignard reagent) with benzophenone in ether.The 1,6-addition products, which come about after dissociation of the radical anion-radical cation pair, show free-radical character as evidenced by the cyclized 1,6-addition products formed in all of the reactions which involve the tertiary probe Grignard reagent (in all solvents studied) with benzophenone and 2-MBP and also in the reaction of the neooctenyl probe Grignard reagent with 2-MBP.