20193-94-6

Basic information

• Product Name: bis[(p-tolyl)methyl] disulphide
• Synonyms: bis[(p-tolyl)methyl] disulphide;Bis(4-methylbenzyl) persulfide;Bis[(4-methylphenyl)methyl] persulfide;Einecs 243-576-0
• CAS NO: 20193-94-6
• Molecular Formula: C₁₆H₁₈S₂
• Molecular Weight: 274.44412
• EINECS: 243-576-0
• Mol File: 20193-94-6.mol
• Article Data: 28

Chemical Properties

• Boiling Point: 398.6°Cat760mmHg
• Flash Point: 220.7°C
• Appearance: /
• Density: 1.127g/cm³
• CAS DataBase Reference: bis[(p-tolyl)methyl] disulphide(CAS DataBase Reference)
• NIST Chemistry Reference: bis[(p-tolyl)methyl] disulphide(20193-94-6)
• EPA Substance Registry System: bis[(p-tolyl)methyl] disulphide(20193-94-6)

Safety Data

• Hazardous Substances Data: 20193-94-6(Hazardous Substances Data)

Upstream product

• 104-81-4 4-Methylbenzyl bromide 
• 72209-88-2 S-(4-methylbenzyl)isothiouronium bromide 
• 65094-22-6 diethyl (bromodifluoromethyl)phosphonate 
• 73789-86-3 4-i-propylbenzyl bromide 
• 589-18-4 4-Methylbenzyl alcohol 
• 68-12-2 N,N-dimethyl-formamide 
• 104-82-5 4-Methylbenzyl chloride 
• 17356-08-0 thiourea 
• 4498-99-1 4-methylbenzylthiol 
• 81067-95-0 4-Methyl-thiobenzylchlorid 
• 18991-39-4 p-methylbenzyl thiocyanate 
• 124-41-4 sodium methylate 
• 3111-52-2 potassium thiophenolate 
• 110-89-4 piperidine 

Downstream Products

• 13250-88-9 bis(4-methylbenzyl)sulfane 
• 1450634-85-1 2-(p-tolyl)thieno[3,2-b]pyridin-3-ol 
• 1450635-19-4 7-methoxy-2-p-tolylthieno[3,2-b]pyridin-3-ol 
• 1576-37-0 N-benzyl-p-toluenesulfonamide 
• 73975-48-1 (α-acetylthio)-p-methylbenzyl p-methylbenzyl sulphoxide 
• 76625-88-2 p-methylbenzyl α-disulfone 
• 104-88-1 4-chlorobenzaldehyde 
• 104-87-0 4-methyl-benzaldehyde 
• 15563-46-9 4-chloro-N,N-dimethylbenzenecarbothioamide 
• 5977-80-0 O-methyl 4-methylbenzenecarbothioate 
• 5925-49-5 O-methyl 4-chlorobenzenecarbothioate 
• 62926-06-1 4-chloro-N-propylbenzenecarbothioamide 
• 1126-46-1 Methyl 4-chlorobenzoate 
• 21011-44-9 4-(4-chloro-thiobenzoyl)-morpholine 

Relevant articles and documents

SULFUR EXTRUSION FROM DISULFIDES BY CARBENES

The present invention relates to a method for preparing a compound T having a thioether group from a compound D having a disulfide group in the presence of a carbene.

Trisulfides over disulfides: Highly selective synthetic strategies, anti-proliferative activities and sustained H2S release profiles

Temperature-and solvent-induced selective synthesis of trisulfides and disulfides is demonstrated. A remarkable selectivity was achieved using Na2S as a sulfur-Transfer agent under mild, greener, catalyst-free and additive-free conditions. This study reveals trisulfides as a better model than disulfides in general for a sustained release of H2S and potent anti-cancer activities.

Conversion of organic halides to disulfanes using KCN and CS2

A sulfur transfer reagent was produced in situ upon stirring a mixture of KCN and CS2 in DMF at r.t. for 15 min, which after heating with an alkyl halide or aryl halide and CuI gave the corresponding symmetric dialkyl or diaryl disulfide, respectively, in high to excellent yields.