2032-24-8

Upstream product

• 76085-56-8 N-(dichloromethyl)methanimidamide hydrochloride 
• 106-47-8 4-chloro-aniline 
• 122-51-0 orthoformic acid triethyl ester 
• 68-12-2 N,N-dimethyl-formamide 
• 100-00-5 4-chlorobenzonitrile 
• 1219-99-4 N,N'-bis(4-chlorophenyl)urea 
• 149-73-5 trimethyl orthoformate 
• 62-53-3 aniline 
• 13506-16-6 N-(4-chloro-phenyl)-formimidic acid ethyl ester 
• 3696-23-9 N-(4-chlorophenyl)thiourea 
• 3696-23-9 p-Cl-phenyl thiocarbamide 
• 54608-54-7 p-chlorophenylformamidine 
• 20265-96-7 p-chloroaniline hydrochloride 
• 100-17-4 para-methoxynitrobenzene 

Downstream Products

• 100733-40-2 (5-methyl-3-oxo-2-o-tolyl-1,2-dihydro-pyrazol-4-yl)-(3-methyl-5-oxo-1-o-tolyl-1,5-dihydro-pyrazol-4-ylidene)-methane 
• 1155-19-7 4-chloro-N-[2-(3-methyl-3H-benzooxazol-2-ylidene)-ethylidene]-aniline 
• 1155-20-0 4-chloro-N-[2-(3-methyl-3H-benzothiazol-2-ylidene)-ethylidene]-aniline 
• 1155-21-1 4-chloro-N-[2-(3-methyl-3H-benzoselenazol-2-ylidene)-ethylidene]-aniline 
• 19375-07-6 4-chloro-N-[2-(3,6-dimethyl-3H-benzo[1,2-d;5,4-d']bisthiazol-2-ylidene)-ethylidene]-aniline 
• 19375-12-3 2,6-bis-[2-(4-chloro-phenylimino)-ethylidene]-3,5-dimethyl-2,3,5,6-tetrahydro-benzo[1,2-d;5,4-d']bisthiazole 
• 49754-67-8 1-(4-Chloro-phenyl)-1-{[(Z)-4-chloro-phenylimino]-methyl}-3,3-dimethyl-urea 
• 128799-85-9 N¹-Tosyl-N¹,N²-di-(p-chlorophenyl)-formamidine 
• 23432-43-1 6-chloro-4-hydroxyquinoline 

Relevant academic research and scientific papers

Method For Preparing Formamidines

A method for preparing formamidines of formula (I) in a single step by reducing ureas of formula (II) using silanes of formula (III), according to reaction (II)+(III)+(I) is provided. The present invention also provides a method for preparing insecticides

Pushing back the limits of hydrosilylation: Unprecedented catalytic reduction of organic ureas to formamidines

Pushing back the limits: A novel catalytic transformation has been designed to prepare formamidine derivatives by reduction of substituted ureas with hydrosilanes. Simple iron catalysts based on commercially available iron salts and phosphine ligands prov

Multicomponent synthesis of 1-aryl 1,2,4-triazoles

A multicomponent (single reactor) process for the synthesis of 1-aryl 1,2,4-triazoles was explored and developed. This transformation prepared the 1,2,4-triazole directly from anilines, amino pyridines, and pyrimidines. The reaction scope was explored with 21 different substrates, and the position of the nitrogen atoms in the newly formed ring was established by 15N labeling and NMR spectroscopy.

Deep eutectic solvent promoted highly efficient synthesis of N, N'-diarylamidines and formamides

A deep eutectic solvent was used as a dual catalyst and reaction medium for the efficient N-formylation of aromatic amines without hazardous organic solvent and catalyst. Treatment of aromatic amines with trimethyl orthoformate and formic acid in deep eutectic solvent at 70 °C gives the corresponding N-formyl derivatives in good to excellent yields. This simple ammonium deep eutectic solvent, easily synthesized from choline chloride and SnCl2, with 100% atom economy and making it applicable to industry and laboratory. Furthermore, heating the trimethyl orthoformate and aromatic primary amines in the deep eutectic solvent results in formation of the corresponding N,N'-diarylamidines in high yields.

Lewis acid catalyst free synthesis of benzimidazoles and formamidines in 1,1,1,3,3,3-hexafluoro-2-propanol

A simple, inexpensive, environmentally friendly and efficient route for the synthesis of benzimidazole and formamidine derivatives by the reaction of O-phenylenediamines or amines with orthoesters using hexafluoroisopropanol as a solvent/catalyst is described.

Formation of Amidines from Aryliminodimagnesium and N,N-Dimethylformamide. Novel Catalytic Mediation by Single Electron Transfer with Use of Nitrobenzenes

N,N'-Diarylformamidines were obtained in good yields by the reaction of aryliminodimagnesium (ArN(MgBr)2) with N,N-dimethylformamide in the presence of nitrobenzene.Novel catalytic mediation by single electron transfer was disclosed.

Raney Nickel Desulphuration of 1-Substituted- and 1,3-Disubstituted-thioureas

Certain 1-aryl-1,3-diaryl- and 1-aryl-3-tetra-O-acetyl-β-D-glucopyranosyl thioureas have been successfully desulphurated into the related mono- and 1,3-di-substituted formamidines with the help of Raney nickel catalyst.A few of them have been converted into the corresponding formamides also.Structure of the products have been established through usual chemical transformations, ir, nmr and mass spectral analysis.

Raney Nickel Desulphuration of Some 1-Arylthioureas

1-Arylthioureas (I) undergo desulphuration in boiling ethanol in the presence of Raney nickel (W-2) to give the corresponding arylformamides (IV) and arylamines (III).A probable mechanism for the formation of these products has been suggested.