20736-42-9

Upstream product

• 451-40-1 phenyl benzyl ketone 
• 78-77-3 Isobutyl bromide 
• 856201-86-0 4-methyl-1,2-diphenylpentane-1,2-diol 
• 4452-11-3 1,2-diphenylprop-2-en-1-one 
• 1888-75-1 isopropyllithium 
• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 3923-51-1 1,1-diphenylprop-2-en-1-ol 
• 78-84-2 isobutyraldehyde 

Downstream Products

• 451-40-1 phenyl benzyl ketone 
• 100-52-7 benzaldehyde 

Relevant academic research and scientific papers

Radical 1,2-Alkylarylation/Acylarylation of Allylic Alcohols with Aldehydes via Neophyl Rearrangement

A metal-free 1,2-alkylarylation of allylic alcohols with aliphatic aldehydes through concomitant radical neophyl rearrangement was developed, providing 1,2-diphenyl-3-alkyl propanones in moderate to good yields. Moreover, when cyclopropanecarbaldehyde and aryl carbaldehydes were concerned, acylarylation was involved leading to 1,4-dicarbonyl compounds.

Studies Dealing with the Cycloreversion Reactions of Phenyl-Substituted 2,3-Diazabicyclohex-2-enes

A study of the reactivity of 2-diazopropane with a series of diphenyl-substituted cyclopropenes has been carried out.The cycloadditions afford 1,5-diphenyl-2,3-diazabicyclohex-2-enes in high yield.Thermolysis of the diazabicyclohexene system for extended periods of time afforded a mixture of 1,3-dienes as well as a substituted bicyclobutane.By studying the distribution of products as a function of time it was possible to show that the 2,3-diazabicyclohexene system first rearranges to an isomeric 1,2-diazabicyclohex-2-ene.This reaction was attributed to an initial cycloreversion to produce a diazoalkene.Attack of the terminal nitrogen atom of the initially generated diazo group onto the neighboring double bond affords the bicyclic aziridine system.Reasonable mechanistic options for the 1,1-cycloaddition include a concerted pathway or a stepwise process.On further heating the 1,2-diazabicyclohexene ring regenerates the allyl-substituted diazoalkane.Loss of nitrogen produces a carbene which undergoes a hydrogen or vinyl shift to give the observed dienes.The formation of the bicyclobutane ring can be viewed in terms of a process involving initial C-N bond cleavage of the 2,3-diazabicyclohexene to yield a diazenyl radical followed by nitrogen loss and radical coupling.In contrast to the thermal results, direct irradiation of the 2,3-diazabicyclohexene results in a cycloreversion to give a 3,4-diaza-substituted 1,3,5-hexatriene derivative.The results obtained indicate that the total mechanistic picture for the thermal and photochemical decomposition of bicyclic pyrazolines can be changed dramatically by the presence of phenyl substituents.