20773-98-2

Basic information

• Product Name: Pyridine, 2-methoxy-, 1-oxide (6CI,7CI,8CI,9CI)
• Synonyms: Pyridine, 2-methoxy-, 1-oxide (6CI,7CI,8CI,9CI);2-methoxy-1-oxidopyridin-1-ium
• CAS NO: 20773-98-2
• Molecular Formula: C₆H₇NO₂
• Molecular Weight: 125.12528
• Product Categories: PYRIDINE
• Mol File: 20773-98-2.mol
• Article Data: 10

Chemical Properties

• Melting Point: 77-78 °C
• Boiling Point: 308.9°C at 760 mmHg
• Flash Point: 140.6°C
• Appearance: /
• Density: 1.09g/cm³
• Vapor Pressure: 0.0012mmHg at 25°C
• Refractive Index: 1.501
• PKA: -0.60±0.10(Predicted)
• CAS DataBase Reference: Pyridine, 2-methoxy-, 1-oxide (6CI,7CI,8CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 2-methoxy-, 1-oxide (6CI,7CI,8CI,9CI)(20773-98-2)
• EPA Substance Registry System: Pyridine, 2-methoxy-, 1-oxide (6CI,7CI,8CI,9CI)(20773-98-2)

Safety Data

• Hazardous Substances Data: 20773-98-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H7NO2/c1-9-6-4-2-3-5-7(6)8/h2-5H,1H3

Upstream product

• 1628-89-3 2-methoxypyridine 
• 93-59-4 Perbenzoic acid 
• 2402-95-1 2-chloropyridine-N-oxide 
• 124-41-4 sodium methylate 
• 3315-60-4 methanolate 
• 67-56-1 methanol 
• 109-09-1 2-chloropyridine 

Downstream Products

• 14395-39-2 2-methoxy-4-nitropyridine N-oxide 
• 1628-89-3 2-methoxypyridine 
• 40775-55-1 1-methoxy-2-pyridone 
• 5446-92-4 2-methoxy-5-nitropyridine 
• 18614-54-5 2-methoxy-4-nitropyridine 
• 96530-77-7 2-methoxy-5-nitropyridine N-oxide 
• 5280-02-4 1-(benzyloxy)pyridin-2(1H)-one 
• 13161-30-3 2-hydroxy-pyridine N-oxide 
• 100367-39-3 4-bromo-2-methoxypyridine 
• 20265-39-8 4-amino-2-methoxypyridine 
• 408502-23-8 2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 
• 29082-97-1 (6-methoxypyridin-2-yl)(phenyl)methanone 

Relevant articles and documents

Method for catalyzing vitamin A isomerization with ruthenium catalyst

The invention provides a method for catalyzing vitamin A isomer conversion with a ruthenium catalyst. According to the method, a ruthenium compound is used as a catalyst, various vitamin A cis-isomerswith low biological activity can be converted into all-trans-isomers with high biological activity in a high proportion in the presence of an auxiliary agent, and the cis-isomers comprise 9-cis-isomers, 11-cis-isomers and 13-cis-isomers. The method has the characteristics of cheap and easily available catalyst, less catalyst dosage, mild reaction conditions, low reaction cost, high isomerizationefficiency and the like.

NICOTINIC RECEPTOR COMPOUNDS

Provided herein are compounds and methods of preparation of compounds that are capable of functioning as agonists or antagonists of a nicotinic receptor. Also provided are pharmaceutical compositions comprising one or more of these compounds, which may further comprise one or more additional therapeutic agents. Further provided are methods of treatment of various conditions that may be responsive to such activity at the nicotinic receptors, such as nicotine dependence.

Experimental and theoretical study of the dissociation enthalpy of the N-O bond on 2-hydroxypyridine N-oxide: Theoretical analysis of the energetics of the N-O bond for hydroxypyrydine N-oxide isomers

The standard (p° = 0.1 MPa) molar enthalpy of formation of crystalline 2-hydroxypyridine N-oxide was measured, at T = 298.15 K, by static bomb calorimetry and the standard molar enthalpy of sublimation, at T = 298.15 K, was obtained using Calvet microcalorimetry. These values were used to derive the standard molar enthalpy of formation of 2-hydroxypyridine N-oxide in gaseous phase, and to evaluate the dissociation enthalpy of the N-O bond. Additionally, high-level density functional theory calculations using the B3LYP hybrid exchange-correlation energy functional have been performed for the three isomers of hydroxypyridine N-oxide in order to confirm the experimental trend for the dissociation enthalpy of the (N-O) bond.