207989-87-5

Basic information

• Product Name: 5-(4-hydroxyphenyl)-2-Pyrrolidinone
• Synonyms: 5-(4-hydroxyphenyl)-2-Pyrrolidinone
• CAS NO: 207989-87-5
• Molecular Weight: 177.203
• Mol File: 207989-87-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 5-(4-hydroxyphenyl)-2-Pyrrolidinone(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-hydroxyphenyl)-2-Pyrrolidinone(207989-87-5)
• EPA Substance Registry System: 5-(4-hydroxyphenyl)-2-Pyrrolidinone(207989-87-5)

Safety Data

• Hazardous Substances Data: 207989-87-5(Hazardous Substances Data)

Usage

Also known as

phenylhydroxybutyric acid lactam

Derivative of

gamma-butyrolactone

Commonly used in

pharmaceutical industry

Uses in pharmaceutical industry

building block in synthesis of various drugs, particularly those related to the central nervous system; precursor for synthesis of certain neurotransmitters; potential applications in treatment of psychiatric and neurological disorders

Exhibits

antioxidant properties

Studied for

potential use in skin care and anti-aging products

Diverse applications in

pharmaceutical and cosmetic industries

Upstream product

• 39662-63-0 5-ethoxy-pyrrolidin-2-one 
• 108-95-2 phenol 
• 7664-93-9 sulfuric acid 
• 128100-35-6 5-(4-methoxyphenyl)pyrrolidin-2-one 
• 100-66-3 methoxybenzene 

Downstream Products

• 899808-28-7 5-[4-(4-phenyl-5-trifluoromethyl-thiophen-2-ylmethoxy)-phenyl]-pyrrolidin-2-one 
• 207989-88-6 γ-4-trifluoromethylsulphonyloxyphenyl-γ-butyrolactam 
• 339087-31-9 4-(5-oxopyrrolidin-2-yl)benzonitrile 
• 899808-41-4 4-carboxymethyl-2-[4-(4-phenyl-5-trifluoromethyl-thiophen-2-ylmethoxy)-phenyl]-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 899808-35-6 5-[4-(4-phenyl-5-trifluoromethyl-thiophen-2-ylmethoxy)-phenyl]-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester 
• 899808-30-1 2-oxo-5-[4-(4-phenyl-5-trifluoromethyl-thiophen-2-ylmethoxy)-phenyl]-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester 
• 899808-36-7 5-[4-(4-phenyl-5-trifluoromethyl-thiophen-2-ylmethoxy)-phenyl]-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 
• 899808-40-3 4-cyanomethyl-2-[4-(4-phenyl-5-trifluoromethyl-thiophen-2-ylmethoxy)-phenyl]-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 899808-39-0 4-iodomethyl-2-[4-(4-phenyl-5-trifluoromethyl-thiophen-2-ylmethoxy)-phenyl]-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 899808-37-8 4-hydroxymethyl-2-[4-(4-phenyl-5-trifluoromethyl-thiophen-2-ylmethoxy)-phenyl]-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 899808-29-8 2-oxo-5-[4-(4-phenyl-5-trifluoromethyl-thiophen-2-ylmethoxy)-phenyl]-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 899808-31-2 2-oxo-5-[4-(4-phenyl-5-trifluoromethyl-thiophen-2-ylmethoxy)-phenyl]-pyrrolidine-3-carboxylic acid ethyl ester 
• 899808-33-4 5-[4-(4-phenyl-5-trifluoromethyl-thiophen-2-ylmethoxy)-phenyl]-pyrrolidine-3-carboxylic acid ethyl ester 
• 461440-95-9 N-tert-butyloxycarbonyl-5-(4-cyanophenyl)-2-pyrrolidinone 

Relevant articles and documents

BIPHENYL DERIVATIVES AS MODULATORS OF THE HISTAMINE-H3 RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO

Biphenyl derivatives of Formula (Ia) and pharmaceutical compositions thereof that modulate the activity of the H3 histamine receptor. (Ia) Compounds of the present invention and pharmaceutical compositions thereof are directed to methods useful in the treatment of histamine H3-associated disorders, such as cognitive disorders, epilepsy, brain trauma, depression, obesity, disorders of sleep and wakefulness, such as narcolepsy, shift-work syndrome, drowsiness as a side effect from a medication, maintenance of vigilance to aid in completion of tasks and the like, cataplexy, hypersomnia, somnolence syndrome, jet lag, sleep apnea and the like, attention deficit hyperactivity disorder (ADHD), schizophrenia, allergies, allergic responses in the upper airway, allergic rhinitis, nasal congestion, dementia, Alzheimer's disease, pain and the like.

2-hetaryl-3,4-dihydro-2H-pyrrole derivatives

The invention relates to novel 2-hetaryl-3,4-dihydro-2H-pyrrole derivatives of the formula (I) in which Hetaryl represents substituted heterocyclyls and Ar represents substituted phenyl, to a plurality of processes for their preparation and to their use a

2-(2-chlorophenyl)-3,4-dihydro-2h-pyrrol derivatives

The invention relates to novel 2-(2-chlorophenyl)-3,4-dihydro-2H-pyrrole derivatives of the formula (I) in which Ar represents substituted phenyl, to a plurality of processes for their preparation and to their use as pesticides.