2082-21-5

Basic information

• Product Name: 1-phenylcycloheptan-1-ol
• Synonyms: 1-phenylcycloheptan-1-ol
• CAS NO: 2082-21-5
• Molecular Formula: C₁₃H₁₈O
• Molecular Weight: 190.28
• Mol File: 2082-21-5.mol
• Article Data: 27

Chemical Properties

• Boiling Point: 312.9°Cat760mmHg
• Flash Point: 122°C
• Appearance: /
• Density: 1.035g/cm³
• Vapor Pressure: 0.000219mmHg at 25°C
• Refractive Index: 1.546
• CAS DataBase Reference: 1-phenylcycloheptan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenylcycloheptan-1-ol(2082-21-5)
• EPA Substance Registry System: 1-phenylcycloheptan-1-ol(2082-21-5)

Safety Data

• Hazardous Substances Data: 2082-21-5(Hazardous Substances Data)

Usage

Structure

Cyclic alcohol with a seven-membered ring and a phenyl group attached to the first carbon

Usage

Synthesis of pharmaceuticals and organic chemicals

Industry Applications

Fragrance and flavor industry, perfumes, and cosmetic products

Odor

Mild, flowery, and sweet

Biological Properties

Potential as an antitumor agent

Pharmacological Properties

Inhibitor of the enzyme acetylcholinesterase, involved in Alzheimer's disease

Industrial and Medicinal Applications

Due to its unique structure and properties, it holds promise for various applications in these fields

InChI:InChI=1/C13H18O/c14-13(10-6-1-2-7-11-13)12-8-4-3-5-9-12/h3-5,8-9,14H,1-2,6-7,10-11H2

Upstream product

• 502-42-1 cycloheptanone 
• 591-51-5 phenyllithium 
• 108-86-1 bromobenzene 
• 3262-89-3 triphenylboroxine 
• 98-80-6 phenylboronic acid 
• 502-41-0 cycloheptanol 
• 5123-13-7 5,5-dimethyl-2-phenyl-1,3,2-dioxaborinane 
• 25308-75-2 1-Phenylcycloheptene 
• 17257-32-8 1-propylcycloheptanol 
• 100-59-4 phenylmagnesium chloride 
• 100-58-3 phenylmagnesium bromide 
• 4401-18-7 phenylcycloheptane 

Downstream Products

• 39162-25-9 Diisopropyl-[2-(1-phenyl-cycloheptyloxy)-ethyl]-amine 
• 110719-01-2 7-iodo-1-phenylheptan-1-one 
• 65-85-0 benzoic acid 
• 1671-75-6 Heptanophenone 
• 37908-41-1 1-hydroperoxy-1-phenylcycloheptane 
• 1195983-81-3 (R)-1-[3-(4-fluorophenyl)-[1,2,4]oxadiazol-5-ylmethyl]-3-(1-phenylcycloheptanecarbonyloxy)-1-azoniabicyclo[2.2.2]octane chloride 
• 1195982-88-7 (R)-3-(1-phenylcycloheptanecarbonyloxy)-1-(2-phenylthiazol-4-ylmethyl)-1-azoniabicyclo[2.2.2]octane chloride 
• 1195983-12-0 (R)-1-(6-methylbenzooxazol-2-ylmethyl)-3-(1-phenylcycloheptanecarbonyloxy)-1-azoniabicyclo[2.2.2]octane chloride 
• 1195982-95-6 (R)-3-(1-phenylcycloheptanecarbonyloxy)-1-(3-phenylisoxazol-5-ylmethyl)-1-azoniabicyclo[2.2.2]octane chloride 
• 1195982-94-5 (R)-3-(1-phenylcycloheptanecarbonyloxy)-1-(5-phenyl-[1,2,4]oxadiazol3-ylmethyl)-1-azoniabicyclo[2.2.2]octane chloride 
• 1195983-03-9 (R)-3-(1-phenylcycloheptanecarbonyloxy)-1-(2-phenyl-oxazol-4-ylmethyl)-1-azoniabicyclo[2.2.2]octane chloride 
• 1195982-98-9 (R)-3-(1-phenylcycloheptanecarbonyloxy)-1-(5-phenylisoxazol-3-ylmethyl)-1-azoniabicyclo[2.2.2]octane chloride 
• 1195982-96-7 (R)-3-(1-phenylcycloheptanecarbonyloxy)-1-(3-phenyl[1,2,4]oxadiazol-5-ylmethyl)-1-azoniabicyclo[2.2.2]octane chloride 
• 1195982-97-8 (R)-3-(1-phenylcycloheptanecarbonyloxy)-1-(5-phenyl-[1,3,4]oxadiazol-2-ylmethyl)-1-azoniabicyclo[2.2.2]octane chloride 

Relevant articles and documents

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Iodobenzene-catalyzed oxidative cleavage of olefins to carbonyl compounds

A metal-free approach for the oxidative cleavage of carbon–carbon double bonds of olefins to carbonyl compounds was established by using oxidant m-CPBA and non-metallic organocatalyst PhI in toluene/H2O. A broad scope of aromatic olefins was used. All the reactions proceeded smoothly at 35 °C in short reaction time to furnish the respective mono- and double carbonyl compounds selectively in moderate to good yields.

Azetidine derivatives and synthesis method thereof

The invention belongs to the field of chemical synthesis, and discloses an azetidine derivative and a synthesis method thereof. The structural formula of the target product azetidine derivatives is asshown in formulae (I), (II), (III), (IV) and (V). The compounds of the formulae are compounds containing an azetidine skeleton, and a nitrogen atom in the skeleton is protected by 2-picolinic acid. The target product azetidine derivatives can be: azetidinyl amide derivatives, azabicyclo[x.1.1] amide derivatives (x=3, 4, 5, 6, 7, 8, 9), azabicyclo[4.1.1] amide derivatives having a substituent at the ring, azabicyclo[4.2.0] amide derivatives and azetidine derivatives containing spirocyclic quaternary carbon. The azetidine derivatives of the present invention have certain protective effect on hydrogen peroxide-induced oxidative stress damage of HC cells.