20846-52-0

Basic information

• Product Name: 2-CHLOROETHANIMIDAMIDE HYDROCHLORIDE
• Synonyms: 2-chloroacetimidamide;2-ChloroacetiMidaMide hydrochloride;Chloromethylcarboxamidine
• CAS NO: 20846-52-0
• Molecular Formula: C₂H₅ClN₂
• Molecular Weight: 92.53
• Mol File: 20846-52-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 146.4°Cat760mmHg
• Flash Point: 42.4°C
• Appearance: /
• Density: 1.38g/cm³
• PKA: 10.18±0.40(Predicted)
• CAS DataBase Reference: 2-CHLOROETHANIMIDAMIDE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLOROETHANIMIDAMIDE HYDROCHLORIDE(20846-52-0)
• EPA Substance Registry System: 2-CHLOROETHANIMIDAMIDE HYDROCHLORIDE(20846-52-0)

Safety Data

• Hazardous Substances Data: 20846-52-0(Hazardous Substances Data)

Usage

General Description

2-Chloroethanimidamide hydrochloride is a chemical compound with the molecular formula C2H6Cl2N2, and it is also known as amino-chloroacetonitrile hydrochloride. It is a water-soluble solid that is often used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is a versatile reagent that is used in various organic reactions, and it can also function as a precursor for the production of other chemical compounds. 2-CHLOROETHANIMIDAMIDE HYDROCHLORIDE is known for its ability to undergo nucleophilic substitution reactions and is commonly used in the production of heterocyclic compounds. Overall, 2-Chloroethanimidamide hydrochloride plays a significant role in the chemical industry as a valuable building block in the synthesis of various important chemicals.

Upstream product

• 41264-52-2 2-chloroethanimidic acid methyl ester 
• 37622-36-9 ethyl chloroacetimidate hydrochloride 
• 107-14-2 chloroacetonitrile 
• 124-42-5 acetamidine hydrochloride 

Downstream Products

• 17467-35-5 3-methyl-1,2,4-thiadiazol-5-amine 
• 944900-08-7 2-(chloromethyl)-5-(trifluoromethyl)pyrimidine 
• 1417917-59-9 2-chloromethyl-3,5,7,8-tetrahydro-pyrano[4,3-d]pyrimidin-4-one 
• 21734-85-0 5-chloro-3-methyl-1,2,4-thiazole 
• 74461-64-6 3-chloromethyl-5-chloro-(1,2,4)-thiadiazole 
• 698-35-1 4-Hydroxy-2-methyl-5-methoxypyrimidine 
• 721958-44-7 2-chloromethyl-5,5-bis(4-fluorophenyl)-3,5-dihydro-imidazol-4-one 

Relevant articles and documents

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4-OXO-3,5,7,8-TETRAHYDRO-4H-PYRANO {4,3-D} PYRMINIDINYL COMPOUNDS FOR USE AS TANKYRASE INHIBITORS

The present invention provides for compounds of formula (I) wherein R1 and R2 are defined herein. The present invention also provides for pharmaceutical compositions and combinations comprising a compound of formula (I) as well as fo

NOVEL 2-PIPERIDIN-1-YL-ACETAMIDE COMPOUNDS FOR USE AS TANKYRASE INHIBITORS

The present invention provides for compounds of formula (I), wherein R1-R5 and L are defined herein. The present invention also provides for pharmaceutical compositions and combinations comprising a compound of formula (I) as well as for the use of such compounds as tankyrase inhibitors and in the treatment of Wnt signaling and tankyrase 1 and 2 signaling related disorders which include, but are not limited to, cancer.