210035-02-2

Basic information

• Product Name: NSC 304613
• Synonyms: Imidazo[1,2-a]pyridin-3-ylphenylmethanone;NSC 304613
• CAS NO: 210035-02-2
• Molecular Formula: C14H10N2O
• Molecular Weight: 222.242
• Mol File: 210035-02-2.mol
• Article Data: 16

Chemical Properties

• Melting Point: 135℃
• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: NSC 304613(CAS DataBase Reference)
• NIST Chemistry Reference: NSC 304613(210035-02-2)
• EPA Substance Registry System: NSC 304613(210035-02-2)

Safety Data

• Hazardous Substances Data: 210035-02-2(Hazardous Substances Data)

Usage

General Description

NSC 304613, also known as 2-Acetylbenzoic acid, is a chemical compound with the molecular formula C9H8O3. It is a derivative of benzoic acid and is commonly used in organic synthesis and as a pharmaceutical intermediate. It is a white to off-white crystalline powder that is sparingly soluble in water but soluble in organic solvents such as ethanol and acetone. NSC 304613 has been found to possess anti-inflammatory and antioxidant properties, and it has been studied for its potential pharmacological applications in the treatment of various diseases. Overall, NSC 304613 is a versatile chemical with a wide range of potential uses in the pharmaceutical and chemical industries.

Upstream product

• 504-29-0 2-aminopyridine 
• 14547-82-1 4-chloro-N-(pyridine-2-yl)benzamide 
• 68-12-2 N,N-dimethyl-formamide 
• 70-11-1 α-bromoacetophenone 
• 57040-75-2 N,N-dimethyl-N'-pyridin-2-yl-formamidine 
• 15753-55-6 (E)-1-phenyl-3-(pyridin-2-ylamino)prop-2-en-1-one 
• 98-86-2 acetophenone 
• 768-03-6 Phenyl vinyl ketone 
• 93-55-0 1-phenyl-propan-1-one 
• 22259-89-8 1-phenyl-3-(pyridin-2-ylamino)propan-1-one 
• 1201-93-0 1-phenyl-3-dimethylaminoprop-2-enone 
• 15753-55-6 (Z)-1-phenyl-3-(pyridin-2-ylamino)prop-2-en-1-one 
• 2579-22-8 Phenylpropargyl aldehyde 
• 1420042-01-8 C₁₄H₁₂N₂ 

Relevant articles and documents

Heterogeneous gold(I)-catalysed annulation between 2-aminopyridines and propiolaldehydes leading to 3-acylimidazo[1,2-a]pyridines

The heterogeneous annulation between 2-aminopyridines and propiolaldehydes was achieved in CH2Cl2 at 25 °C in the presence of 3 mol% of MCM-41-immobilised phosphine gold(I) complex (MCM-41-PPh3-AuCl) and AgSbF6

Fe-Catalyzed enaminone synthesis from ketones and amines

We have developed an iron-catalyzed direct olefination for enaminone synthesis, with saturated ketones as a source of olefins. This direct ketone β-functionalization reaction has readily available starting materials and a wide range of substrates and requires mild reaction conditions.

I2-catalyzed intramolecular oxidative amination of C(sp3)-H bond: Efficient access to 3-acylimidazo[1,2-: A] pyridines under neat condition

An efficient and "green" protocol for the synthesis of 3-acylimidazo[1,2-a]pyridines through intramolecular oxidative α-amination of carbonyl compounds has been developed. The reaction proceeds smoothly utilizing I2 as a catalyst and H2O2 as an oxidant under neat condition with broad substrate scope. Several complex nitrogen-containing fused rings are conveniently constructed, which are not easy to access by traditional methods.