21240-37-9

Basic information

• Product Name: 1,4-Benzenedibutanol
• Synonyms: 4,4'-(1,4-phenylene)dibutan-1-ol;4-[4-(4-hydroxybutyl)phenyl]butan-1-ol;1,4-Benzenedibutanol;4,4-(1,4-Phenylene)bis(butan-1-ol)
• CAS NO: 21240-37-9
• Molecular Formula: C₁₄H₂₂O₂
• Molecular Weight: 222.32328
• Mol File: 21240-37-9.mol
• Article Data: 6

Chemical Properties

• Melting Point: 61-63 °C(Solv: benzene (71-43-2))
• Boiling Point: 387.4±35.0 °C(Predicted)
• Appearance: /
• Density: 1.028±0.06 g/cm3(Predicted)
• PKA: 14.85±0.10(Predicted)
• CAS DataBase Reference: 1,4-Benzenedibutanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Benzenedibutanol(21240-37-9)
• EPA Substance Registry System: 1,4-Benzenedibutanol(21240-37-9)

Safety Data

• Hazardous Substances Data: 21240-37-9(Hazardous Substances Data)

Usage

General Description

1,4-Benzenedibutanol is a compound that consists of a benzene ring with two butanol groups attached at the 1 and 4 positions, hence the name. It is used as a chemical intermediate in the production of plasticizers, resins, and other industrial materials. It has the potential to act as an endocrine disruptor, affecting hormonal systems in animals, and has been shown to have toxic effects on aquatic organisms. Additionally, it is considered a hazardous substance and should be handled and disposed of with care. Overall, 1,4-Benzenedibutanol is an important industrial chemical with potential risks to environmental and human health.

Upstream product

• 624-38-4 para-diiodobenzene 
• 4542-72-7 1,4-bis-(2-bromoethyl)benzene 
• 5140-03-4 2-[4-(2-hydroxyethyl)phenyl]ethan-1-ol 
• 36076-25-2 (4-methoxycarbonylmethylphenyl)acetic acid methyl ester 
• 7325-46-4 1,4-phenylenediacetic acid 
• 22339-61-3 γ-(p-succinylphenyl)butyric acid 
• 22339-62-4 4-[4-(3-carboxypropyl)phenyl]butyric acid 
• 134519-88-3 4,4'-(1,4-phenylene)bis(but-3-yn-1-ol) 
• 85784-83-4 4-[4-(3-Ethoxycarbonyl-propyl)-phenyl]-butyric acid ethyl ester 
• 6337-65-1 4-[4-(3-methoxycarbonylpropyl)phenyl]butyric acid methyl ester 

Downstream Products

• 2778-48-5 1,4-bis-(4-bromobutyl)benzene 
• 900186-19-8 6,6'-(1,4-phenylene)bis[2-(dimethylsulfanylidene)hexanal] 
• 900186-26-7 6,6'-(1,4-phenylene)bis[2-(methylthio)hexanal] 
• 900186-21-2 4,4'-(1,4-phenylene)dibutyl dimesylate 
• 832688-84-3 1,4-bis(4-oxobutyl)benzene 
• 853261-37-7 4,4'-(1,4-phenylene)dibutyl diiodie 
• 131169-39-6 4,4'-(1,4-phenylene)bis(butane-4,1-diyl)bis(4-methylbenzene sulfonate) 
• 343588-18-1 1,4-bis-(5,5-dicarboxy-pentyl)-benzene 
• 201138-69-4 6,6'-p-phenylene-di-hexanoic acid dimethyl ester 
• 134520-11-9 6,6'-p-phenylene-di-hexanoic acid 
• 6544-06-5 <12>paracyclophane 
• 85784-85-6 1,4-bis<4-(2-formylphenoxy)butyl>benzene 

Relevant articles and documents

FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS AND THEIR USE FOR THE PREVENTION OR TREATMENT OF DISEASE

This invention provides compounds of Formulae (IA), (IB), (IC), (ID), (IE), (IF), (IG), (IH), (IJ), (IK), (IL), (II), (III), (IIIA), and (IIIB); pharmaceutically acceptable salts and solvates thereof; and compositions thereof. This invention further provides methods for treating a disease, including but not limited to, liver disease or an abnormal liver condition; cancer (such as hepatocellular carcinoma or cholangiocarcinoma); a malignant or benign tumor of the lung, liver, gall bladder, bile duct or digestive tract; an intra- or extra-hepatic bile duct disease; a disorder of lipoprotein; a lipid-and-metabolic disorder; cirrhosis; fibrosis; a disorder of glucose metabolism; a cardiovascular or related vascular disorder; a disease resulting from steatosis, fibrosis, or cirrhosis; a disease associated with increased inflammation (such as hepatic inflammation or pulmonary inflammation); hepatocyte ballooning; a peroxisome proliferator activated receptor-associated disorder; an ATP citrate lyase disorder; an acetyl-coenzyme A carboxylase disorder; obesity; pancreatitis; or renal disease.

Bis-azaaromatic quaternary ammonium salts as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release: An investigation of binding conformation

A series of conformationally restricted bis-azaaromatic quaternary ammonium salts (3 and 4) have been designed and synthesized in order to investigate the possible binding conformations of N,N′-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB; 2), a

Synthesis of planar-chiral paracyclophanes via samarium(II)-catalyzed intramolecular pinacol coupling

(Chemical Equation Presented) A series of [n]jparacyclophanediols (n = 8-12) was synthesized by samarium-catalyzed pinacol coupling for their ansa-bridge formation. Enantiomerically pure [n]jparacyclophane esters were derived from the diols in a several steps via chiral resolution (for n = 10) or via crystallization-induced asymmetric transformation (for n = 11) by using amino alcohol auxiliaries and their selective cleavages.