6337-65-1

Basic information

• Product Name: methyl 4-[4-(3-methoxycarbonylpropyl)phenyl]butanoate
• CAS NO: 6337-65-1
• Molecular Formula: C₁₆H₂₂O₄
• Molecular Weight: 278.348
• Mol File: 6337-65-1.mol

Chemical Properties

• CAS DataBase Reference: methyl 4-[4-(3-methoxycarbonylpropyl)phenyl]butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-[4-(3-methoxycarbonylpropyl)phenyl]butanoate(6337-65-1)
• EPA Substance Registry System: methyl 4-[4-(3-methoxycarbonylpropyl)phenyl]butanoate(6337-65-1)

Safety Data

• Hazardous Substances Data: 6337-65-1(Hazardous Substances Data)

Upstream product

• 7325-46-4 1,4-phenylenediacetic acid 
• 36076-25-2 (4-methoxycarbonylmethylphenyl)acetic acid methyl ester 
• 5140-03-4 2-[4-(2-hydroxyethyl)phenyl]ethan-1-ol 
• 4542-72-7 1,4-bis-(2-bromoethyl)benzene 
• 22339-61-3 γ-(p-succinylphenyl)butyric acid 
• 67-56-1 methanol 
• 22339-62-4 4-[4-(3-carboxypropyl)phenyl]butyric acid 
• 105-06-6 1,4-Divinylbenzene 
• 2365-48-2 Methyl thioglycolate 

Downstream Products

• 54622-09-2 p-Bis(4-chlor-4-methylpentyl)benzol 
• 38864-78-7 3-tert-Butyl-7-[4-(5-tert-butyl-5-hydroxy-4,4-dimethyl-hept-6-ynyl)-phenyl]-4,4-dimethyl-hept-1-yn-3-ol 
• 38864-75-4 p-Bis(4,4,6,6-tetramethyl-5-oxoheptyl)benzol 
• 343588-18-1 1,4-bis-(5,5-dicarboxy-pentyl)-benzene 
• 201138-69-4 6,6'-p-phenylene-di-hexanoic acid dimethyl ester 
• 882654-00-4 4,4'-(cis-cyclohexane-1,4-diyl)-di-butyric acid 
• 134520-11-9 6,6'-p-phenylene-di-hexanoic acid 
• 6544-06-5 <12>paracyclophane 
• 54622-08-1 p-Bis(4-hydroxy-4-methylpentyl)benzol 
• 21240-37-9 4-[4-(4-hydroxybutyl)phenyl]butan-1-ol 
• 6337-63-9 4,4'-(trans-cyclohexane-1,4-diyl)-di-butyric acid dimethyl ester 
• 6337-63-9 4,4'-(cis-cyclohexane-1,4-diyl)-di-butyric acid dimethyl ester 

Relevant articles and documents

FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS AND THEIR USE FOR THE PREVENTION OR TREATMENT OF DISEASE

This invention provides compounds of Formulae (IA), (IB), (IC), (ID), (IE), (IF), (IG), (IH), (IJ), (IK), (IL), (II), (III), (IIIA), and (IIIB); pharmaceutically acceptable salts and solvates thereof; and compositions thereof. This invention further provides methods for treating a disease, including but not limited to, liver disease or an abnormal liver condition; cancer (such as hepatocellular carcinoma or cholangiocarcinoma); a malignant or benign tumor of the lung, liver, gall bladder, bile duct or digestive tract; an intra- or extra-hepatic bile duct disease; a disorder of lipoprotein; a lipid-and-metabolic disorder; cirrhosis; fibrosis; a disorder of glucose metabolism; a cardiovascular or related vascular disorder; a disease resulting from steatosis, fibrosis, or cirrhosis; a disease associated with increased inflammation (such as hepatic inflammation or pulmonary inflammation); hepatocyte ballooning; a peroxisome proliferator activated receptor-associated disorder; an ATP citrate lyase disorder; an acetyl-coenzyme A carboxylase disorder; obesity; pancreatitis; or renal disease.

Reductive C-C Coupling by Desulfurizing Gold-Catalyzed Photoreactions

[Au2(μ-dppm)2]Cl2-mediated photocatalysis reactions are usually initiated by ultraviolet A (UVA) light; herein, an unreported system using blue light-emitting diodes (LEDs) as excitation light source was found. The red shift of the absorption wavelength originates from the combination of [Au2(μ-dppm)2]Cl2 and ligand (Ph3P or mercaptan). On the basis of this finding, a gold-catalyzed reductive desulfurizing C-C coupling of electrophilic radicals and styrenes mediated by blue LEDs is presented, a coupling which cannot be efficiently accessed by previously reported methods. This mild and highly efficient C-C bond formation strategy uses mercaptans both as electron-deficient alkyl radical precursor as well as the hydrogen source. Two examples of amino acids have also been modified by using this strategy. Moreover, this methodology could be applied in polymer synthesis. Gram-scale synthesis and mechanistic insights into this transformation are also presented.