21617-15-2

Basic information

• Product Name: 7-chloro-2,3-dihydro-4-quinolone
• Synonyms: 7-chloro-2,3-dihydro-4-quinolone;7-Chloro-2,3-dihydroquinolin-4(1H)-one;4(1H)-Quinolinone, 7-chloro-2,3-dihydro-;7-CHLORO-1,2,3,4-TETRAHYDROQUINOLIN-4-ONE;7-chloro-2,3-dihydro-1H-quinolin-4-one
• CAS NO: 21617-15-2
• Molecular Formula: C9H8ClNO
• Molecular Weight: 181.61892
• EINECS: 244-481-7
• Mol File: 21617-15-2.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 340.8°C at 760 mmHg
• Flash Point: 159.9°C
• Appearance: /
• Density: 1.29g/cm³
• Vapor Pressure: 8.42E-05mmHg at 25°C
• Refractive Index: 1.579
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 7-chloro-2,3-dihydro-4-quinolone(CAS DataBase Reference)
• NIST Chemistry Reference: 7-chloro-2,3-dihydro-4-quinolone(21617-15-2)
• EPA Substance Registry System: 7-chloro-2,3-dihydro-4-quinolone(21617-15-2)

Safety Data

• Hazardous Substances Data: 21617-15-2(Hazardous Substances Data)

Usage

General Description

7-chloro-2,3-dihydro-4-quinolone is a chemical compound that falls within a group of structurally similar compounds known as quinolones. Quinolones are significant due to their extensive use as antibiotics in the medical field. This particular chemical, 7-chloro-2,3-dihydro-4-quinolone, shares a basic structure of a bicyclic ring system with other quinolones but has unique characteristics due to its specific substitution patterns. It is a synthetic compound with significant biological activity, used for its antimicrobial and antiviral properties. Toxicity and safety profiles of 7-chloro-2,3-dihydro-4-quinolone are important considerations for its use in pharmaceutical applications.

InChI:InChI=1/C9H8ClNO/c10-6-1-2-7-8(5-6)11-4-3-9(7)12/h1-2,5,11H,3-4H2

Upstream product

• 625-99-0 3-iodochlorobenzene 
• 7664-93-9 sulfuric acid 
• 21617-14-1 3-(m-chloroanilino)-propionic acid 
• 21617-13-0 ethyl 3-(3-chlorophenylamino)propanoate 
• 108-42-9 3-chloro-aniline 
• 155250-02-5 methyl N-(3-chlorophenyl)-N-<(4-methylphenyl)sulfonyl>-β-alaninate 
• 66737-56-2 N-(3-chlorophenyl)-N-<(4-methylphenyl)sulfonyl>-β-alanine 
• 42313-47-3 methyl N-(3-chlorophenyl)-β-alaninate 
• 76227-98-0 1-(3-chlorophenyl)-azetidin-2-one 
• 66820-85-7 7-chloro-1-(toluene-4-sulfonyl)-2,3-dihydro-1H-quinolin-4-one 
• 26413-49-0 1-acetyl-7-chloro-2,3-dihydro-1H-quinolin-4-one 

Downstream Products

• 81099-86-7 4-[(7-chloroquinolin-4-yl)amino]phenol 
• 83674-18-4 (7-chloroquinolin-4-yl)-phenyl-amine 
• 86-99-7 7-chloro-4-hydroxylquinoline 
• 116792-06-4 3-chloro-8-methoxy-11H-indolo<3,2-c>quinoline 
• 155249-55-1 3-Chloro-11-phenyl-11H-indolo[3,2-c]quinoline 
• 34374-22-6 NSC 317605 
• 611-36-9 quinolin-4-ol 

Relevant articles and documents

HETEROCYCLIC COMPOUND

The present invention relates to a compound which can be useful for the treatment or prevention of SPT-related diseases including cancer and congenital diseases associated with sphingolipid accumulation (including Niemann-Pick disease).

Structure-activity relationships of antimalarial indoloquinolines

Structure-activity relationships have been ascertained and chemical metodology developed for a series of antimalarial 3-chloroindoloquinoline-5-oxides.The basic side chain as well as the ring N-oxide are critical for antimalarial activity as is a bromine or chlorine in position 3.Substitution at positions 7,8,9,10 in not essential, although the most potent analog in our studies was the 8-nitro compound 4vv. indoloquinolines / antimalarial agents

Ring-expansion of some heterocyclic β-ketoesters with dimethyl acetylene dicarboxylate. Part 2

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