219716-49-1

Basic information

• Product Name: [[2-(2-propyn-1-yloxy)ethoxy]methyl]benzene
• Synonyms: [[2-(2-propyn-1-yloxy)ethoxy]methyl]benzene
• CAS NO: 219716-49-1
• Molecular Weight: 190.242
• Mol File: 219716-49-1.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: [[2-(2-propyn-1-yloxy)ethoxy]methyl]benzene(CAS DataBase Reference)
• NIST Chemistry Reference: [[2-(2-propyn-1-yloxy)ethoxy]methyl]benzene(219716-49-1)
• EPA Substance Registry System: [[2-(2-propyn-1-yloxy)ethoxy]methyl]benzene(219716-49-1)

Safety Data

• Hazardous Substances Data: 219716-49-1(Hazardous Substances Data)

Usage

General Description

The chemical compound [2-(2-propyn-1-yloxy)ethoxy]methyl]benzene is a complex organic compound featuring a benzene ring attached to a functional group containing propyne and ethoxy moieties. The molecule consists of a benzene ring with a propyne group attached to one of its carbon atoms, and an ethoxy group connected to the propyne via an oxygen atom. In addition, the ethoxy group is further linked to a methyl group, resulting in a highly branched structure. [[2-(2-propyn-1-yloxy)ethoxy]methyl]benzene may have potential applications in organic synthesis and material science due to its unique structure and reactivity.

Upstream product

• 3973-18-0 2-(prop-2-ynyloxy)ethanol 
• 100-44-7 benzyl chloride 
• 622-08-2 2-Benzyloxyethanol 
• 106-96-7 propargyl bromide 
• 100-39-0 benzyl bromide 

Downstream Products

• 869310-70-3 1-cyclopropyl-4-oxo-6-[3-({2-[(phenylmethyl)oxy]ethyl}oxy)-1-propyn-1-yl]-1,4-dihydro-3-quinolinecarboxylic acid 
• 869310-80-5 4-oxo-6-[3-({2-[(phenylmethyl)oxy]ethyl}oxy)-1-propyn-1-yl]-1-(2-propen-1-yl)-1,4-dihydro-3-quinolinecarboxylic acid 
• 869310-65-6 1-ethyl-4-oxo-6-[3-({2-[(phenylmethyl)oxy]ethyl}oxy)-1-propyn-1-yl]-1,4-dihydro-3-quinolinecarboxylic acid 
• 1251931-78-8 1-ethyl-4-oxo-6-[3-({2-[(phenylmethyl)oxy]ethyl}oxy)propyl]-1,4-dihydro-3-quinolinecarboxylic acid 

Relevant articles and documents

Discovery of highly potent, selective, and brain-penetrant aminopyrazole Leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitors

Leucine-rich repeat kinase 2 (LRRK2) has drawn significant interest in the neuroscience research community because it is one of the most compelling targets for a potential disease-modifying Parkinson's disease therapy. Herein, we disclose structurally div

CYANOINDOLINE DERIVATIVES AS NIK INHIBITORS

Fused aromatic bicyclic substituted 5-(2-amino-4-pyrimidinyl)- cyanoindoline derivatives (I) useful for therapy and/or prophylaxis in a mammal, and in particular to inhibitors of NF-KB-inducing kinase (NIK - also known as MAP3K14) useful for treating diseases such as cancer, inflammatory disorders, metabolic disorders and autoimmune disorders. The invention is also directed to pharmaceutical compositions comprising such compounds, and to the use of such compounds or pharmaceutical compositions for the prevention or treatment of diseases such as cancer, inflammatory disorders, metabolic disorders including obesity and diabetes, and autoimmune disorders.

Synthesis and biological activity of 4″-O-acyl derivatives of 14- and 15-membered macrolides linked to ω-quinolone-carboxylic unit

The synthesis and antimicrobial activity of a new class of macrolide antibiotics which consist of a macrolide scaffold and a quinolone unit covalently connected by an appropriate linker are described. Optimization of several synthetic steps and structural