2216-99-1

Basic information

• Product Name: 2-Hydroxy-3-methoxy-5-(2-propenyl)benzoic acid
• Synonyms: 2-Hydroxy-3-methoxy-5-(2-propenyl)benzoic acid;5-Allyl-2-hydroxy-3-Methoxybenzoic acid
• CAS NO: 2216-99-1
• Molecular Formula: C₁₁H₁₂O₄
• Molecular Weight: 208.21
• Mol File: 2216-99-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Hydroxy-3-methoxy-5-(2-propenyl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Hydroxy-3-methoxy-5-(2-propenyl)benzoic acid(2216-99-1)
• EPA Substance Registry System: 2-Hydroxy-3-methoxy-5-(2-propenyl)benzoic acid(2216-99-1)

Safety Data

• Hazardous Substances Data: 2216-99-1(Hazardous Substances Data)

Upstream product

• 97-53-0 4-allylguaiacol 
• 298-14-6 potassium hydrogencarbonate 
• 96619-89-5 3-methoxy-2-(2-propenyloxy)benzoic acid, methyl ester 
• 6342-70-7 3-methoxymethylsalicylate 
• 877-22-5 3-methoxysalicylic acid 
• 124-38-9 carbon dioxide 
• 96619-88-4 2-(allyloxy)-3-methoxybenzoic acid 
• 85614-43-3 2-hydroxy-3-methoxy-5-(2-propeny)benzoic acid, methyl ester 

Downstream Products

• 13990-88-0 2-hydroxy-3-methoxy-5-propylbenzoic acid 
• 1229610-98-3 (E)-2-hydroxy-3-methoxy-5-(prop-1-enyl)benzoic acid 
• 97-53-0 4-allylguaiacol 
• 124-38-9 carbon dioxide 

Relevant articles and documents

PROCESS FOR PREPARING SYNTHETIC PARA-EUGENOL

Processes are provided for preparing synthetic para-eugenol and polysiloxane- polycarbonate copolymers including the synthetic para-eugenol. In an embodiment, a process for synthesizing para-eugenol can comprise: a) hydrolyzing methyl 5-allyl-3- methoxysalicylate to form 5-allyl-3-methoxysalicylic acid; b) decarboxylating the 5-allyl-3- methoxysalicylic acid to form a product comprising para-eugenol. The polysiloxane- polycarbonate copolymer prepared by the process may be isolated by, for example, anti- solvent precipitation followed by vacuum drying.

Regioselective ortho-carboxylation of phenols catalyzed by benzoic acid decarboxylases: A biocatalytic equivalent to the Kolbe-Schmitt reaction

The enzyme catalyzed carboxylation of electron-rich phenol derivatives employing recombinant benzoic acid decarboxylases at the expense of bicarbonate as CO2 source is reported. In contrast to the classic Kolbe-Schmitt reaction, the biocatalytic equivalent proceeded in a highly regioselective fashion exclusively at the ortho-position of the phenolic directing group in up to 80% conversion. Several enzymes were identified, which displayed a remarkably broad substrate scope encompassing alkyl, alkoxy, halo and amino- functionalities. Based on the crystal structure and molecular docking simulations, a mechanistic proposal for 2,6-dihydroxybenzoic acid decarboxylase is presented.