22543-74-4

Basic information

• Product Name: 4-TERT-BUTYLBENZHYDROL
• Synonyms: 4-TERT-BUTYLBENZHYDROL
• CAS NO: 22543-74-4
• Molecular Formula: C₁₇H₂₀O
• Molecular Weight: 240.34
• Mol File: 22543-74-4.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-TERT-BUTYLBENZHYDROL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-TERT-BUTYLBENZHYDROL(22543-74-4)
• EPA Substance Registry System: 4-TERT-BUTYLBENZHYDROL(22543-74-4)

Safety Data

• Hazardous Substances Data: 22543-74-4(Hazardous Substances Data)

Upstream product

• 939-97-9 4-tert-Butylbenzaldehyde 
• 100-58-3 phenylmagnesium bromide 
• 3972-65-4 1-bromo-4-tert-butylbenzene 
• 100-52-7 benzaldehyde 
• 104-87-0 4-methyl-benzaldehyde 
• 98-80-6 phenylboronic acid 
• 769-92-6 4-tert-Butylaniline 
• 98-54-4 para-tert-butylphenol 
• 52458-10-3 1-tert-Butyl-4-(phenylmethoxy)benzene 
• 100-39-0 benzyl bromide 
• 100-59-4 phenylmagnesium chloride 
• 100-44-7 benzyl chloride 
• 52866-85-0 4-tert-butylphenyllithium 

Downstream Products

• 1450760-27-6 (E)-ethyl 3-(4-tert-butylphenyl)-3-phenylacrylate 
• 1450760-15-2 (E)-3-(4-tert-butylphenyl)-N-[3-fluoro-4-(methylsulfonamido)benzyl]-3-phenylacrylamide 
• 1610046-01-9 C₁₉H₂₀O₂ 
• 1426146-55-5 (R)-(4-tert-butylphenyl)(phenyl)methyl acetate 
• 1334474-85-9 (4-(tert-butyl)phenyl)(phenyl)methyl acetate 
• 124419-93-8 2-Brom-1,3-bis(4-tert-butylphenyl)-1,3-diphenyl-1-propen 
• 124419-83-6 1,3-Bis(4-tert-butylphenyl)-1,3-diphenyl-1-propen 
• 22679-54-5 4-tert-butylbenzophenone 
• 16251-99-3 1-benzyl-4-tert-butylbenzene 
• 574-42-5 benzhydryl ether 
• 136908-17-3 1-(Benzhydryloxy-phenyl-methyl)-4-tert-butyl-benzene 
• 136908-28-6 C₃₄H₃₈O 
• 116597-11-6 1,2-bis(4-tert-butylphenyl)-1,2-diphenylethane-1,2-diol 
• 38651-12-6 Brom(4-tert-butylphenyl)phenylmethan 

Relevant articles and documents

Bio-inspired asymmetric aldehyde arylations catalyzed by rhodium-cyclodextrin self-inclusion complexes

Transition-metal catalysts are powerful tools for carbon-carbon bond-forming reactions that are difficult to achieve using native enzymes. Enzymes that exhibit inherent selectivities and reactivities through host-guest interactions have inspired widesprea

Direct allylation of benzyl alcohols, diarylmethanols, and triarylmethanols mediated by XtalFluor-E

We report the direct allylation of benzyl alcohols, diarylmethanols and triarylmethanols mediated by XtalFluor-E using allyltrimethylsilane. The resulting allylated products are obtained in moderate to high yield.

Design, synthesis and biological evaluation of B-region modified diarylalkyl amide analogues as novel TRPV1 antagonists

Design, synthesis and biological evaluation of B-region, known to be a dipolar interacting pharmacophore, modified diarylalkyl amide analogues for novel TRPV1 (transient receptor potential channel, vanilloid subfamily member 1) antagonists was described. A variety of moieties including guanidines, heterocyclic rings, cinnamides, and α-substituted acetamides were introduced at the B-region. TRPV1 antagonistic activities of these analogues were evaluated by 45Ca2+ uptake assay in rat DRG neuron. In particular, α,α-difluoroamide 53 exhibited 3-fold more potent TRPV1 antagonistic activity (IC50 = 0.058 μM) than the parent amide analogue 6.