22731-65-3Relevant articles and documents
Asymmetric Catalytic Epoxidation of Terminal Enones for the Synthesis of Triazole Antifungal Agents
Feng, Xiaoming,He, Qianwen,Liu, Xiaohua,Zhang, Dong,Zhang, Fengcai
supporting information, p. 6961 - 6966 (2021/09/11)
An enantioselective epoxidation of α-substituted vinyl ketones was realized to construct the key epoxide intermediates for the synthesis of various triazole antifungal agents. The reaction proceeded efficiently in high yields with good enantioselectivities by employing a chiral N,N′-dioxide/ScIII complex as the chiral catalyst and 35% aq. H2O2 as the oxidant. It enabled the facile transformation for optically active isavuconazole, efinaconazole, and other potential antifungal agents.
The cation exchange resin-promoted coupling of alkynes with aldehydes: one-pot synthesis of α,β-unsaturated ketones
Yadav,Subba Reddy,Vishnumurthy
, p. 4498 - 4500 (2008/09/21)
Alkynes undergo smooth coupling with aldehydes in the presence of Amberlyst-15 at room temperature to produce the corresponding α,β-unsaturated ketones in high yields with E-geometry. The use of an inexpensive, readily available, and recyclable cation exchange resin makes this method quite simple and convenient.
INSECTICIDAL TETRAHYDROINDENOPYRIDINE DERIVATIVES
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Page/Page column 13; 24, (2008/06/13)
Certain tetrahydroindenylpyridine derivatives provide unexpected insecticidal and acaricidal activity. These compounds are represented by formula (I); wherein R, R1, R2, and R3 are fully described herein. In addition, comp
