22803-05-0

Basic information

• Product Name: 3,3',4,4'-Biphenyltetracarboxylic acid
• Synonyms: BPDA;3,3',4,4'-BIPHENYLTETRACARBOXYLIC ACID;[1,1'-BIPHENYL]-3,3',4,4'-TETRACARBOXYLIC ACID;Biphenyl-3,3',4,4'-tetracarboxylicacid;3,34,4-BIPHENYL TETRACARBOXYLIC ACID,99% MIN;3,3',4,4'-[1,1'-Biphenyl]tetracarboxylic acid;3,4,3',4'-Biphenyltetracarboxylic acid;4,4'-Biphthalic acid
• CAS NO: 22803-05-0
• Molecular Formula: C₁₆H₁₀O₈
• Molecular Weight: 330.25
• EINECS: 2017-001-1
• Product Categories: Organic acids
• Mol File: 22803-05-0.mol
• Article Data: 11

Chemical Properties

• Melting Point: >300 C
• Boiling Point: 673.3 °C at 760 mmHg
• Flash Point: 375 °C
• Appearance: /
• Density: 1.612 g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.80±0.10(Predicted)
• CAS DataBase Reference: 3,3',4,4'-Biphenyltetracarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3',4,4'-Biphenyltetracarboxylic acid(22803-05-0)
• EPA Substance Registry System: 3,3',4,4'-Biphenyltetracarboxylic acid(22803-05-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 22803-05-0(Hazardous Substances Data)

Usage

General Description

3,3',4,4'-Biphenyltetracarboxylic acid, also known as Tetracarboxybiphenyl, is an organic compound that is derived from biphenyl. It is a white or almost white, crystalline powder with a sharp, faintly aromatic odor. 3,3',4,4'-Biphenyltetracarboxylic acid consists of two phenyl rings connected by single bonds with a carboxylic acid group at each ring corner, making it a tetracarboxylic acid. Its molecular formula is C14H10O8. Generally, it is used in chemical and pharmaceutical research, and in the synthesis of new materials due to its potential to form supramolecular structures. Handling this substance should always be done with caution because it can cause skin irritation, serious eye damage, and may also be harmful if ingested or inhaled.

Upstream product

• 63297-02-9 3,3′-dimethylbiphenyl-4,4′-dicarboxylic acid 
• 63197-17-1 N-methyl-4-chlorophthalimide 
• 14074-63-6 3,3’,4,4’-biphenyltetracarboxylic diimide 
• 26491-49-6 4-chloro-N-phenyl phthalimide 
• 613-33-2 (4,4'-dimethyl-1,1'-biphenyl) 
• 85-44-9 phthalic anhydride 
• 56047-23-5 monosodique de l'acide chloro-4 phtalique 
• 4920-95-0 3,4,3',4'-Tetramethylbiphenyl 
• 615-60-1 4-chloro-1,2-dimethylbenzene 
• 583-71-1 4-bromo-o-xylene 
• 7500-55-2 dimethyl cyclohex-4-ene-1,2-dicarboxylate 
• 1352221-13-6 3,4-dimethoxycarbonylcyclohexyl-3′,4′-dimethylbenzene 
• 1371598-38-7 3,4-dicarbomethoxybiphenyl-3',4'-dicarboxylic acid anhydride 
• 1371598-37-6 3,4-dicarbomethoxybiphenyl-3',4'-dicarboxylic acid 

Downstream Products

• 92-52-4 biphenyl 
• 2420-87-3 3,3',4,4'-biphenyltetracarboxylic anhydride 

Relevant articles and documents

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Method for preparing biphenyldianhydride through microwave-assisted catalytic coupling

The invention discloses a method for preparing biphenyldianhydride through microwave-assisted catalytic coupling. In a green solvent 2 - methyltetrahydrofuran (2-THF) system, under microwave irradiation, under microwave irradiation, under a temperature 60 - 95 °C condition, the reaction time is over 20-60 minutes to prepare a biphenyl derivative, and after hydrolysis and dehydration, biphenyldianhydride is obtained. The present invention is characterized in that an organometallic complex is formed by using a halogenated monomer having a complexing action, and zinc halide generated by the reaction with the reaction. It is avoided that its deposition on the reducing agent metal surface results in a reduction in its reducing ability. Compared with the traditional method for preparing the same biphenyl dianhydride, the method is high in reaction speed, the reducing agent is close to the quantitative reaction, and the cost is lower.

Synthesis method for 3,3',4,4'-biphenyltetracarboxylic acid

The invention discloses a synthesis method for 3,3',4,4'-biphenyltetracarboxylic acid. The synthesis method comprises the following steps: with 4,4'-dimethyl biphenyl as a starting raw material, subjecting the 4,4'-dimethyl biphenyl and cyclic anhydride as shown in a formula I which is described in the specification to a Friedel-Crafts acylation reaction so as to obtain an intermediate II, and carrying out an oxidation reaction so as to obtain the 3,3',4,4'-biphenyltetracarboxylic acid, wherein the cyclic anhydride as shown in the formula I is selected from the group consisting of succinic anhydride, glutaric anhydride, adipic anhydride and maleic anhydride. The method provided by the invention does not need an expensive catalytic system, so the production cost of synthesizing the 3,3',4,4'-biphenyltetracarboxylic acid is greatly reduced; the method provided by the invention is simple to operate, mild in reaction conditions, less in three wastes, easy in wastewater treatment and friendly to the environment; and the raw material, namely the 4,4'-dimethyl biphenyl adopted in the method provided by the invention is a byproduct of a medical intermediate, namely sartan biphenyl, and theproduction amount of the byproduct accounts for about 10% of the production amount of the sartan biphenyl, so the waste can be turned into treasure after the byproduct is applied to synthesis of the3,3',4,4'-biphenyltetracarboxylic acid.