63197-17-1

Basic information

• Product Name: 5-chloro-2-methyl-1H-isoindole-1,3(2H)-dione
• Synonyms: 1H-isoindole-1,3(2H)-dione, 5-chloro-2-methyl-; 5-Chloro-2-methyl-1H-isoindole-1,3(2H)-dione
• CAS NO: 63197-17-1
• Molecular Formula: C₉H₆ClNO₂
• Molecular Weight: 195.6024
• Mol File: 63197-17-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 315.5°C at 760 mmHg
• Flash Point: 144.6°C
• Density: 1.454g/cm³
• Vapor Pressure: 0.000435mmHg at 25°C
• Refractive Index: 1.619
• CAS DataBase Reference: 5-chloro-2-methyl-1H-isoindole-1,3(2H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-2-methyl-1H-isoindole-1,3(2H)-dione(63197-17-1)
• EPA Substance Registry System: 5-chloro-2-methyl-1H-isoindole-1,3(2H)-dione(63197-17-1)

Safety Data

• Hazardous Substances Data: 63197-17-1(Hazardous Substances Data)

Upstream product

• 14737-08-7 4-chloro-1,2,3,6-tetrahydrophthalic anhydride 
• 74-89-5 methylamine 
• 3676-85-5 4-aminophthalimide 
• 89-40-7 4-nitrophthalimide 
• 136918-14-4 phthalimide 
• 7147-90-2 4-chlorophthalimide 
• 74-88-4 methyl iodide 
• 118-45-6 4-chlorophthalic anhydride 
• 2307-00-8 4-amino-N-methylphthalimide 

Downstream Products

• 80993-19-7 4-Chloro-2-(3-methoxy-2,2,3-trimethyl-butyryl)-N-methyl-benzamide 
• 80993-15-3 5-Chloro-2-(3-methoxy-2,2,3-trimethyl-butyryl)-N-methyl-benzamide 
• 1185-55-3 Methyltrimethoxysilan 
• 22803-05-0 4,4'-biphthalic acid 
• 36978-40-2 2,3,3′,4′-biphenyl tetracarboxylic dianhydride 
• 5566-47-2 N-methyl-4-chloro-5-nitrophthalimide 
• 63197-24-0 4-phenoxy-N-methyl phthalimide 

Relevant articles and documents

Two new isomerous fluorescent chemosensors for Al3+ based on photoinduced electron transfer

Two new isomerous PET fluorescent chemosensors (L and L') for Al 3+ have been designed, synthesized and characterized. The two chemosensors exhibited fluorescence enhancement upon binding Al3+ in CH3-CN by PET inhibition processes from both the sulfur and the nitrogen donors to anthracene. The job's plot, Benesi-Hildebrand plot and 1H NMR titration experiments indicate that both chemosensors form a 1: 1 complex with Al3+. The binding constants were calculated to be (1.432 ±0.186) × 105 and (1.427 ± 0.970) × 105, respectively. Furthermore, the lowest detection limit for Al3+ in CH3CN was determined to be 4.8 × 10 7 M and 2.2 × 10 7 M, respectively.

Isoindol - 1, 3 - dione compound and its preparation method and application (by machine translation)

The invention discloses a isoindole - 1, 3 - dione compound and its preparation method and application. The general formula (I) has the structure shown. The invention of the isoindole - 1, 3 - diones to LNCap cells with cell inhibitory activity, can be used for preparing anti-tumor drug. (by machine translation)

PREPARATION OF SUBSTITUTED PHTHALIC ANHYDRIDE, ESPECIALLY 4-CHLOROPHTALIC ANHYDRIDE

A method for the synthesis of substituted phthalic anhydrides (IV) wherein R' is a halogen, aromatic or aliphatic group comprising 1-18 carbons, hydrogen or nitro group is the transimidation between a substituted N-alkyl phthalimide (V) wherein R is an alkyl having from 1 to 18 carbons, and a substituted tetrahydrophthalic anhydride (VI): The by product of this reaction, a substituted N-alkyl tetrahydrophthalimide (VII), may be converted by aromatization to the substituted N-alkyl phthalimide (V).