23439-91-0

Basic information

• Product Name: 2,2-dimethyl-1-phenyl-1-propanol
• Synonyms: 2,2-dimethyl-1-phenyl-1-propanol
• CAS NO: 23439-91-0
• Molecular Weight: 164.247
• Mol File: 23439-91-0.mol
• Article Data: 166

Chemical Properties

• CAS DataBase Reference: 2,2-dimethyl-1-phenyl-1-propanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-dimethyl-1-phenyl-1-propanol(23439-91-0)
• EPA Substance Registry System: 2,2-dimethyl-1-phenyl-1-propanol(23439-91-0)

Safety Data

• Hazardous Substances Data: 23439-91-0(Hazardous Substances Data)

Upstream product

• 677-22-5 tert-butylmagnesium chloride 
• 100-52-7 benzaldehyde 
• 3835-64-1 2,2-dimethyl-1-phenylpropan-1-ol 
• 97-72-3 2-Methylpropionic anhydride 
• 1078-58-6 diphenylzinc 
• 630-19-3 pivalaldehyde 
• 938-16-9 2,2-dimethylpropiophenone 
• 30070-63-4 meta-chlorobenzoic anhydride 
• 123-62-6 propionic acid anhydride 
• 113775-62-5 <2R-(2α(S^*),3aα,4β,7β,7aα)>-2-(2,2-Dimethyl-1-phenylpropoxy)-octahydro-7,8,8-trimethyl-4,7-methanobenzofuran 
• 98-80-6 phenylboronic acid 
• 108-86-1 bromobenzene 
• 38111-44-3 phenylzinc(II) bromide 
• 802294-64-0 propionic acid 

Downstream Products

• 100895-65-6 (-)-(S)-(1-chloro-2,2-dimethylpropyl)benzene 
• 70712-85-5 (S)-1-bromo-2,2-dimethyl-1-phenyl-propane 
• 82323-56-6 (R)-(+)-α-phenylneopentyl chloride 
• 136476-07-8 (E)-3-((S)-2,2-Dimethyl-1-phenyl-propoxy)-2-methyl-propenal 
• 136476-06-7 (E)-3-((R)-2,2-Dimethyl-1-phenyl-propoxy)-2-methyl-propenal 
• 1040199-21-0 (1S,5S)-1,5-di(tert-butyl)-1,5-diphenyl-2,4-dioxapentane 
• 1040199-25-4 (1S,7S)-1,7-di(tert-butyl)-1,7-diphenyl-2,4,6-trioxaheptane 
• 1040199-29-8 (1S,9S)-1,9-di(tert-butyl)-1,9-diphenyl-2,4,6,8-tetraoxanonane 
• 1040199-34-5 (1S,11S)-1,11-di(tert-butyl)-1,11-diphenyl-2,4,6,8,10-pentaoxaundecane 
• 1040199-38-9 (1S,13S)-1,13-di(tert-butyl)-1,13-diphenyl-2,4,6,8,10,12-hexaoxatridecane 
• 175522-76-6 [(R)-2,2-Dimethyl-1-((E)-2-methyl-buta-1,3-dienyloxy)-propyl]-benzene 
• 136476-14-7 [(S)-2,2-Dimethyl-1-((E)-2-methyl-buta-1,3-dienyloxy)-propyl]-benzene 
• 100702-91-8 (R)-(-)-1,1,2-triphenyl-3,3-dimethylbutane 
• 1688-17-1 (S)-(-)-α-phenylneopentyl chloride 

Relevant articles and documents

Rhodium(I)-, iridium(I)-, and ruthenium(II)-catalyzed asymmetric transfer hydrogenation of ketones using diferrocenyl dichalcogenides as chiral ligands

[R,S;R,S]-Bis[2-[1-(dimethylamino)ethyl]ferrocenyl] dichalcogenides, (R,S)-{[EC5H3CHMe(NMe2)]Fe(C5H5)}2 (E = S, Se, Te), act as chiral ligands for Rh(I)-catalyzed asymmetric transfer hydrog

Manganese catalyzed asymmetric transfer hydrogenation of ketones

The asymmetric transfer hydrogenation (ATH) of a wide range of ketones catalyzed by manganese complex as well as chiral PxNy-type ligand under mild conditions was investigated. Using 2-propanol as hydrogen source, various ketones could be enantioselectively hydrogenated by combining cheap, readily available [MnBr(CO)5] with chiral, 22-membered macrocyclic ligand (R,R,R',R')-CyP2N4 (L5) with 2 mol% of catalyst loading, affording highly valuable chiral alcohols with up to 95% ee.

PQXdpap: Helical Poly(quinoxaline-2,3-diyl)s Bearing 4-(Dipropylamino)pyridin-3-yl Pendants as Chirality-Switchable Nucleophilic Catalysts for the Kinetic Resolution of Secondary Alcohols

Helically chiral poly(quinoxaline-2,3-diyl)s bearing 4-(dipropylamino)pyridin-3-yl pendants at the 5-position of the quinoxaline ring (PQXdpap) exhibited high catalytic activities and moderate to high selectivities (up to s = 87) in the acylative kinetic resolution of secondary alcohols. The solvent-dependent helical chirality switching of PQXdpap between pure toluene and a 1:1 mixture of toluene and 1,1,2-trichloroethane enabled the preparation of either compound of a pair of enantiomerically pure alcohols (>99% ee) from a single catalyst.

RETRACTED ARTICLE: The Manganese(I)-Catalyzed Asymmetric Transfer Hydrogenation of Ketones: Disclosing the Macrocylic Privilege

The bis(carbonyl) manganese(I) complex [Mn(CO)2(1)]Br (2) with a chiral (NH)2P2 macrocyclic ligand (1) catalyzes the asymmetric transfer hydrogenation of polar double bonds with 2-propanol as the hydrogen source. Ketones (43 substrates) are reduced to alcohols in high yields (up to >99 %) and with excellent enantioselectivities (90–99 % ee). A stereochemical model based on attractive CH–π interactions is proposed.