23839-33-0

Basic information

• Product Name: 2-THIOCYANATO-CYCLOHEXANONE
• Synonyms: 2-THIOCYANATO-CYCLOHEXANONE
• CAS NO: 23839-33-0
• Molecular Formula: C₇H₉NOS
• Molecular Weight: 155.22
• Mol File: 23839-33-0.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-THIOCYANATO-CYCLOHEXANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-THIOCYANATO-CYCLOHEXANONE(23839-33-0)
• EPA Substance Registry System: 2-THIOCYANATO-CYCLOHEXANONE(23839-33-0)

Safety Data

• Hazardous Substances Data: 23839-33-0(Hazardous Substances Data)

Upstream product

• 108-94-1 cyclohexanone 
• 1147550-11-5 ammonium thiocyanate 
• 7677-24-9 trimethylsilyl cyanide 
• 333-20-0 potassium thioacyanate 
• 1056477-06-5 2-bromocyclohexanone 
• 2290-65-5 trimethylsilyl isothiocyanate 

Downstream Products

• 438568-89-9 2-bromo-4,5,6,7-tetrahydrobenzo[d]thiazole 
• 26846-98-0 2-Chlor-4,5,6,7-tetrahydro-benzothiazol 
• 57001-13-5 4,5,6,7-tetrahydro-2-benzothiazolinone 

Relevant articles and documents

One-pot synthesis using supported reagents system: Conversion of β-dicarbonyl compounds to α-thiocyano-β-dicarbonyl compounds using CuBr2/Al2O3-KSCN/SiO2

Transformation of β-dicarbonyl compound 1 to α-thiocyano-α-dicarbonyl compounds 3 in one-pot was achieved by using supported reagents system CuBr2/Al2O3 - KSCN/SiO2, in which 1 reacts first with CuBr2/Al2O3 and the product, α-bromo-β-dicarbonyl compound 2 reacts with KSCN/SiO2 to give the final product 3 in good yield.

Graphene oxide: A promising carbocatalyst for the regioselective thiocyanation of aromatic amines, phenols, anisols and enolizable ketones by hydrogen peroxide/KSCN in water

Graphene oxide (GO), as a heterogeneous carbocatalyst, catalyzes the direct thiocyanation of a variety of arenes including aromatic amines, phenols, anisols and carbonyl compounds that possessing α-hydrogen in the presence of hydrogen peroxide and KSCN in water as a green media. This procedure is chemoselective, avoids the use of precious metals and toxic solvents and has a broad substrate scope. Easy removal from the reaction mixture and recyclability with no loss of activity are the key features of graphene oxide in this catalytic system.

A convenient, rapid, and general synthesis of α-oxo thiocyanates using clay supported ammonium thiocyanate

A very rapid, convenient, and general method for the synthesis of α-oxo thiocyanates has been described by using clay supported ammonium thiocyanate. The procedure avoids the use of additional catalyst, solvent, aqueous work-up and the yields are high. Moreover, the method is applicable for a variety of aryl, heteroaryl, alkyl α-halo carbonyls, β-keto tosylates, α-halo β-dicarbonyl, α-tosyl, β-dicarbonyl, alkyl halide, and alkyl tosylates.