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24210-19-3

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24210-19-3 Usage

General Description

CBZ-L-Valine Methyl Ester is a chemical compound that is often used in the synthesis of various pharmaceuticals and peptides. It is an ester derivative of the amino acid L-valine, with a carbobenzyloxy (CBZ) group attached to the amino group. CBZ-L-VALINE METHYL ESTER is commonly used in the protection and manipulation of amino acid residues in peptide synthesis. It is also used in the preparation of various pharmaceutical products and in the research and development of new drugs. Additionally, it is a valuable intermediate in the production of other chemicals and compounds. Overall, CBZ-L-Valine Methyl Ester plays a crucial role in the pharmaceutical and chemical industries due to its versatile applications in synthesis and production.

Check Digit Verification of cas no

The CAS Registry Mumber 24210-19-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,2,1 and 0 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 24210-19:
(7*2)+(6*4)+(5*2)+(4*1)+(3*0)+(2*1)+(1*9)=63
63 % 10 = 3
So 24210-19-3 is a valid CAS Registry Number.

24210-19-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl (2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoate

1.2 Other means of identification

Product number -
Other names Cbz-valine methyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:24210-19-3 SDS

24210-19-3Relevant articles and documents

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Miyoshi

, p. 1489,1490,1494 (1973)

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Green Esterification of Carboxylic Acids Promoted by tert-Butyl Nitrite

Cheng, Xionglve,Jiang, Gangzhong,Li, Xingxing,Tao, Suyan,Wan, Xiaobing,Zhao, Yanwei,Zheng, Yonggao

supporting information, p. 2713 - 2718 (2021/06/25)

In this work, the green esterification of carboxylic acids promoted by tert-butyl nitrite has been well developed. This transformation is compatible with a broad range of substrates and exhibits excellent functional group tolerance. Various drugs and substituted amino acids are applicable to this reaction under near neutral conditions, with good to excellent yields.

α-Amino Aldehydes as Readily Available Chiral Aldehydes for Rh-Catalyzed Alkyne Hydroacylation

Hooper, Joel F.,Seo, Sangwon,Truscott, Fiona R.,Neuhaus, James D.,Willis, Michael C.

supporting information, p. 1630 - 1634 (2016/02/20)

Readily available α-amino aldehydes, incorporating a methylthiomethyl (MTM) protecting group on nitrogen, are shown to be efficient substrates in Rh-catalyzed alkyne hydroacylation reactions. The reactions are performed under mild conditions, employing a small-bite-angle bis-phosphine ligand, allowing for good functional group tolerance with high stereospecificity. Amino aldehydes derived from glycine, alanine, valine, leucine, phenylalanine, isoleucine, serine, tryptophan, methionine, and cysteine were successfully employed, as was an enantiomerically enriched α-OMTM-aldehyde derived from phenyllactic acid. The synthetic utility of the α-amino enone products is demonstrated in a short enantioselective synthesis of the natural product sphingosine.

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