138754-84-4Relevant articles and documents
Discovery of (Dihydro)pyrazine N-Oxides via Genome Mining in Pseudomonas
Kretsch, Ashley M.,Morgan, Gina L.,Tyrrell, Jillian,Mevers, Emily,Vallet-Gély, Isabelle,Li, Bo
, p. 4791 - 4795 (2018)
Overexpression of the Pseudomonas virulence factor (pvf) biosynthetic operon led to the identification of a family of pyrazine N-oxides (PNOs), including a novel dihydropyrazine N,N′-dioxide (dPNO) metabolite. The nonribosomal peptide synthetase responsib
Synthetic method of key intermediate Tuv of natural anti-cancer drug Tubulysins
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Paragraph 0064; 0091; 0093, (2020/08/06)
The invention belongs to the technical field of chemical synthesis, and particularly relates to a synthesis method of a key intermediate Tuv of a natural anti-cancer drug Tubulysins. With L-valinol (1) which is cheap and easy to obtain as a raw material,
FUMAGILLOL COMPOUNDS AND METHODS OF MAKING AND USING SAME
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Paragraph 00146, (2018/03/06)
Disclosed herein, in part, are fumagillol compounds and methods of use in treating medical disorders, such as obesity. Pharmaceutical compositions and methods of making fumagillol compounds are provided. The compounds are contemplated to have activity against methionyl aminopeptidase 2.