24284-35-3

Basic information

• Product Name: 5-chloro-3-hydroxy-3-phenyl-3H-indol-2-one
• Synonyms: 5-chloro-3-hydroxy-3-phenyl-3H-indol-2-one
• CAS NO: 24284-35-3
• Molecular Weight: 259.692
• Mol File: 24284-35-3.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 5-chloro-3-hydroxy-3-phenyl-3H-indol-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-3-hydroxy-3-phenyl-3H-indol-2-one(24284-35-3)
• EPA Substance Registry System: 5-chloro-3-hydroxy-3-phenyl-3H-indol-2-one(24284-35-3)

Safety Data

• Hazardous Substances Data: 24284-35-3(Hazardous Substances Data)

Upstream product

• 17630-76-1 5-chloroindole 2,3-dione 
• 98-80-6 phenylboronic acid 
• 1417819-68-1 1-azido-4-chloro-2-(phenylethynyl)benzene 
• 23746-76-1 5-chloro-2-phenylindole 
• 841-76-9 triphenylaluminium 
• 108-86-1 bromobenzene 
• 100-58-3 phenylmagnesium bromide 

Downstream Products

• 24279-55-8 2-amino-5-chloro-3-hydroxy-3-phenylindole 
• 1243153-56-1 C₃₂H₂₅ClN₂OSi 
• 1243153-55-0 N-allyl-5-chloro-3-hydroxy-3-phenylindol-2-amine 
• 15815-97-1 5-chloro-3-phenyl-2-indolinone 
• 1243153-73-2 (S)-5-chloro-3-hydroxy-3-phenylindolin-2-one 
• 1243153-75-4 (S)-2-amino-5-chloro-3-hydroxy-3-phenylindole 
• 719-59-5 5-chloro-2-aminobenzophenone 
• 1399290-75-5 tert-butyl 5-chloro-2-oxo-3-phenylindoline-1-carboxylate 
• 77014-77-8 5-Chloro-1-(4-chloro-benzoyl)-3-imidazol-1-yl-3-phenyl-1,3-dihydro-indol-2-one 
• 77014-75-6 1-Benzoyl-5-chloro-3-imidazol-1-yl-3-phenyl-1,3-dihydro-indol-2-one 
• 77015-03-3 1-Acetyl-5-chloro-3-imidazol-1-yl-3-phenyl-1,3-dihydro-indol-2-one 

Relevant articles and documents

One-Pot Synthesis of 2-Aminobenzophenones from 2-Alkynyl Arylazides Catalyzed by Pd and Cu Precursors

We describe a novel one-pot three-step reaction of 2-alkynyl arylazides through palladium-catalyzed formation of 3-hydroxy-3-phenylindolin-2-ones followed by hydrolysis of amide bonds and copper-catalyzed decarboxylation to give 2-aminobenzophenones. This synthetic method works well with various 2-alkynyl arylazides and affords the products in moderate to good yields under mild reaction conditions.

Preparation process of 3-peroxy-2-indolone compound in water phase

The invention relates to a preparation process of a 3-peroxy-2-indolone compound. The method comprises the steps of adopting a 2-indolone derivative as a raw material and water as a reaction solvent for a reaction with tert-butanol peroxide at a certain t

C(sp 3)-H Peroxidation of 3-Substituted Indolin-2-ones under Metal-Free Conditions

A C(sp 3)-H peroxidation of 3-substituted indolin-2-ones through radical coupling reaction has been developed under metal-free conditions. Using tert -butyl hydroperoxide both as an oxidant and as a peroxidation reagent to couple with the C(sp 3)-H bonds of 3-substituted indolin-2-ones can form a new C-O bond without using any additives. This simple strategy provides a green and efficient approach to 3-peroxyindolin-2-ones in moderate to excellent yields. The resulting 3-peroxyindolin-2-ones could be further transformed into 3-hydroxyindolin-2-ones.