24707-99-1Relevant articles and documents
Selective Acetylation of Non-anomeric Groups of per- O-Trimethylsilylated Sugars
Weldu, Welday Desta,Wang, Cheng-Chung
, p. 5336 - 5344 (2021/04/02)
Selective modification of the hydroxyl groups of sugars has been a long-standing challenge due to their proximate relative reactivity. Herein, we report a TMSOTf-catalyzed selective acetylation of the non-anomeric hydroxyl groups of several per-O-TMS-protected sugar substrates while leaving their anomeric group unaffected. In addition to standing versatile by itself, the anomeric O-TMS group left intact can be functionalized to afford key sugar precursors such as imidate donors, which could otherwise be synthesized via a stepwise anomeric deprotection-functionalization procedure.
Development of a Novel Method for Trimethylsilylation of Saccharides?
Chen, Jyun-Siao,Ke, Yi-Fan,Lin, Heng-Yan,Lin, Wesley,Yen, Wei-Chung,Wu, Hsin-Ru,Luo, Shun-Yuan
, p. 2000 - 2006 (2021/02/01)
The trimethylsilyl (TMS) group is widely used in carbo?hydrate synthesis, although this protecting group is unstable and its post-synthetic purification challenging. The successful trimethylsilyl?ation of carbohydrates mediated by recyclable and efficient
A palladium-catalyzed approach to allenic aromatic ethers and first total synthesis of terricollene A
Cui, Yifan,Huang, Chaofan,Li, Can,Lin, Jie,Liu, Qi,Ma, Shengming,Qin, Anni,Shi, Fuchun,Wang, Huanan,Wu, Guolin,Wu, Penglin,Xiao, Junzhe,Xu, Haibo,Yu, Biao,Yuan, Yuan,Zhai, Yizhan,Zheng, Wei-Feng,Zheng, Yangguangyan
, p. 9347 - 9351 (2021/07/25)
A palladium-catalyzed C-O bond formation reaction between phenols and allenylic carbonates to give 2,3-allenic aromatic ethers with decent to excellent yields under mild reaction conditions has been described. A variety of synthetically useful functional
