247133-32-0

Basic information

• Product Name: 1,4-Piperidinedicarboxylic acid, 4-(2-hydroxyethyl)-, 1-(1,1-diMethylethyl) 4-ethyl ester
• Synonyms: 1,4-Piperidinedicarboxylic acid, 4-(2-hydroxyethyl)-, 1-(1,1-diMethylethyl) 4-ethyl ester;4-(2-Hydroxyethyl)-1,4-Piperidinedicarboxylic Acid 1-(1,1-DiMethylethyl) 4-Ethyl Ester
• CAS NO: 247133-32-0
• Molecular Formula: C₁₅H₂₇NO₅
• Molecular Weight: 302.38652
• Product Categories: Aromatics, Heterocycles
• Mol File: 247133-32-0.mol

Chemical Properties

• Boiling Point: 390.5°C at 760 mmHg
• Flash Point: 189.9°C
• Appearance: /
• Density: 1.106g/cm³
• Vapor Pressure: 1.03E-07mmHg at 25°C
• Refractive Index: 1.483
• PKA: 15.10±0.10(Predicted)
• CAS DataBase Reference: 1,4-Piperidinedicarboxylic acid, 4-(2-hydroxyethyl)-, 1-(1,1-diMethylethyl) 4-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Piperidinedicarboxylic acid, 4-(2-hydroxyethyl)-, 1-(1,1-diMethylethyl) 4-ethyl ester(247133-32-0)
• EPA Substance Registry System: 1,4-Piperidinedicarboxylic acid, 4-(2-hydroxyethyl)-, 1-(1,1-diMethylethyl) 4-ethyl ester(247133-32-0)

Safety Data

• Hazardous Substances Data: 247133-32-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1,4-Piperidinedicarboxylic acid, 4-(2-hydroxyethyl)-, 1-(1,1-dimethylethyl) 4-ethyl ester is used as an intermediate in the synthesis of various pharmaceutical compounds for its ability to be modified and incorporated into different drug molecules.
Used in Chemical Synthesis:
In the chemical industry, 1,4-Piperidinedicarboxylic acid, 4-(2-hydroxyethyl)-, 1-(1,1-dimethylethyl) 4-ethyl ester is used as a building block for the creation of more complex molecules, taking advantage of its reactive functional groups and structural features.
Used in Research and Development:
This piperidine derivative is also utilized in research and development settings, where it can be studied for its potential applications in various fields, such as material science, drug discovery, and chemical engineering.

InChI:InChI=1/C15H27NO5/c1-5-20-12(18)15(8-11-17)6-9-16(10-7-15)13(19)21-14(2,3)4/h17H,5-11H2,1-4H3

Upstream product

• 247133-31-9 1-tert-butoxycarbonyl-4-ethoxycarbonylpiperidin-4-ylacetic acid 
• 142851-03-4 1-tert-butyl 4-ethyl piperidine-1,4-dicarboxylate 
• 146603-99-8 1-(1,1-dimethylethyl) 4-ethyl 4-(2-propenyl)-1,4-piperidinedicarboxylate 

Downstream Products

• 374791-95-4 2-(3,5-bis-trifluoromethyl-phenyl)-N-[4-(2-oxa-8-aza-spiro[4.5]dec-8-yl)-1-phenyl-cyclohexyl]-propionamide 
• 374791-95-4 2-(3,5-bis-trifluoromethyl-phenyl)-N-[4-(2-oxa-8-aza-spiro[4.5]dec-8-yl)-1-phenyl-cyclohexyl]-propionamide 
• 236406-38-5 1,1-dimethylethyl 4-(2-hydroxyethyl)-4-(hydroxymethyl)-1-piperidinecarboxylate 
• 374794-96-4 1,1-dimethylethyl 2-oxa-8-azaspiro[4,5]decane-8-carboxylate 
• 176-69-2 2-oxa-8-azaspiro[4.5]decane 
• 4427-25-2 2-oxa-8-aza-spiro[4.5]decan-1-one 
• 154348-08-0 1,1-dimethylethyl 1-oxo-2-oxa-8-azaspiro[4,5]decane-8-carboxylate 

Relevant articles and documents

Amidine compounds

A compound of the formula [I] wherein R1, R2and R3are the same or different and each is hydrogen atom, wherein each symbol is as defined in the specification, a salt thereof or a prodrug thereof. The compound of the presen

4,4-Disubstituted cyclohexylamine NK1 receptor antagonists II

A series of novel 4,4-disubstituted cyclohexylamines as NK1 receptor antagonists is described: modifications to the amine moiety retain NK1 receptor binding affinity whilst disrupting IKr affinity.