25111-96-0Relevant articles and documents
Iridium(III) complex-coated nanosystem for ratiometric upconversion luminescence bioimaging of cyanide anions
Liu, Jinliang,Liu, Yi,Liu, Qian,Li, Chunyan,Sun, Lining,Li, Fuyou
, p. 15276 - 15279 (2011)
Chromophoric iridium(III) complex-coated NaYF4: 20%Yb, 1.6%Er, 0.4%Tm nanocrystals are demonstrated as a ratiometric upconversion luminescence (UCL) probe for highly selective detection of cyanide anion and bioimaging of CN- in living cells through inhibition of the energy transfer from the UCL of the nanocrystals to the absorbance of the chromophoric complex. The UCL probe provides a very low detection limit of 0.18 μM CN- in the aqueous solution.
Synthesis and evaluation of biological activities of bis(Spiropyrazolone)cyclopropanes: A potential application against Leishmaniasis
Barreiro-Costa, Olalla,Morales-Noboa, Gabriela,Rojas-Silva, Patricio,Lara-Barba, Eliana,Santamaría-Aguirre, Javier,Bailón-Moscoso, Natalia,Romero-Benavides, Juan Carlos,Herrera, Ana,Cueva, Cristina,Ron-Garrido, Lenin,Poveda, Ana,Heredia-Moya, Jorge
, (2021/08/30)
This work focuses on the search and development of drugs that may become new alternatives to the commercial drugs currently available for treatment of leishmaniasis. We have designed and synthesized 12 derivatives of bis(spiropyrazolone)cyclopropanes. We
Synthesis of some pyrazolone derivatives and evaluation of its antibacterial and cytotoxic activity
Parajuli, Rishiram,Banerjee, Janmajoy,Khanal, Hemanta
, p. 2099 - 2106 (2016/02/27)
A series of novel pyrazolone derivative were synthesized by two different schemes (scheme-1 by the reaction of phenyl hydrazine and ethyl acetoacetate with substituted benzaldehydes PYR-1 to PYR-4) and (by the reaction of synthesized chalcone with phenyl hydrazine PYR-5) and characterised with its physical parameters (M.P, colour, %yield, solubility etc.). The entire synthesized compound was tested for their antimicrobial activity against Grampositive and Gram-negative strains of bacteria and brimeshrimp bioassay was conducted for evaluation of cytotoxic activity The Investigation of antimicrobial screening data revealed that most of the tested compounds showed moderate to good antimicrobial activity. And cytotoxicity activity of compounds was also found to be satisfactory.