252966-52-2Relevant academic research and scientific papers
Effective activation of the chiral salen/Ti(OiPr)4 catalyst with achiral phenolic N-oxides as additives in the enantioselective cyanosilylation of ketones
He, Bin,Chen, Fu-Xue,Li, Yan,Feng, Xiaoming,Zhang, Guolin
, p. 4657 - 4666 (2004)
The activation of chiral titanium(IV) complexes with phenolic N-oxides additives has been found to provide an alternative strategy for the asymmetric cyanosilylation of ketones. By using 10 mol % of chiral salen-titanium(IV) complex in combination with 1
Asymmetric cyanosilylation of ketones catalyzed by novel chiral N,N′-dioxide titanium complexes
Li, Qinghan,Liu, Xiaohua,Wang, Jun,Shen, Ke,Feng, Xiaoming
, p. 4011 - 4014 (2006)
A novel C2-symmetric chiral N,N′-dioxide titanium complex was described, which could efficiently catalyze the asymmetric cyanosilylation of ketones in high yields with up to 92% ee under mild conditions. In addition, the catalyst system was sim
Asymmetric addition of trimethylsilyl cyanide to ketones catalyzed by Al(salen)/triphenylphosphine oxide
Kim, Sung Soo,Kwak, Ju Myung
, p. 49 - 53 (2006)
Trimethylsilyl cyanide asymmetrically adds to various ketones by catalysis of 1/triphenylphosphine oxide. This is a double activation where 1 acts as Lewis acid and Ph3PO Lewis base. Various ketones were subjected to the enantioselective additi
Enantioselective cyanosilylation of ketones by a catalytic double-activation method with an aluminium complex and an N-oxide
Chen, Fu-Xue,Zhou, Hui,Liu, Xiaohua,Qin, Bo,Feng, Xiaoming,Zhang, Guolin,Jiang, Yaozhong
, p. 4790 - 4797 (2004)
Double-activation catalysis promises high catalytic efficiency in the enantioselective cyanosilylation of ketones through the combined use of a Lewis acid and a Lewis base. Catalyst systems composed of a chiral salen-Al complex and an N-oxide have high ca
Discrete versus in situ-generated aluminum-salen catalysts in enantioselective cyanosilylation of ketones: Role of achiral ligands
Alaaeddine, Ali,Roisnel, Thierry,Thomas, Christophe M.,Carpentiera, Jean-Francois
, p. 731 - 740 (2008)
The monometallic species {Salen}AlX (X=Me, 2a,b; X=Cl, 4a,b; O-i-Pr, 5a,b) and open bimetallic species {Salen}[AlMe2]2 (3a,b) that result from binary combinations between an aluminum precursor [trimethylaluminum, dimethylaluminum chl
Enantioselective cyanosilylation of ketones by a catalytic double-activation method employing chiral lewis acid and achiral N-oxide catalysts
Chen, Fuxue,Feng, Xiaoming,Qin, Bo,Zhang, Guolin,Jiang, Yaozhong
, p. 949 - 952 (2003)
(Matrix presented). Enantioselective addition of TMSCN to ketones is achieved by a catalytic double-activation method using 1a-Ti(IV) complex as the Lewis acid and achiral N-oxide 2 as the Lewis base to activate ketones and TMSCN, respectively.
Catalytic asymmetric cyanosilylation of ketones by a chiral amino acid salt
Liu, Xiaohua,Qin, Bo,Zhou, Xin,He, Bin,Feng, Xiaoming
, p. 12224 - 12225 (2005)
In this Communication, we describe the first highly enantioselective cyanosilylation of ketones catalyzed by simple chiral amino acid salt. A broad range of aromatic, α,β-unsaturated, heterocyclic ketones catalyzed by L-phenylglycine sodium salt gave the
Enantioselective cyanosilylation of ketones catalyzed by Mn(salen)/Ph3PO
Kim, Sung Soo,Lee, Sang Hyuck,Kwak, Ju Myung
, p. 1165 - 1169 (2006)
TMSCN asymmetrically adds to a variety of ketones by catalysis with 1/Ph3PO. This is a double activation where 1 acts as a Lewis acid and Ph3PO as a Lewis base. Various ketones were subjected to the enantioselective addition to give
The asymmetric addition of trimethylsilyl cyanide to ketones catalysed by a bimetallic, chiral (salen)titanium complex
Belokon, Yuri N.,Green, Brendan,Ikonnikov, Nicolai S.,North, Michael,Tararov, Vitali I.
, p. 8147 - 8150 (1999)
The use of a bimetallic titanium salen complex as a catalyst for the asymmetric addition of trimethylsilylcyanide to ketones is reported. The cyanohydrin trimethylsilyl ethers are obtained with enantiomeric excesses of up to 72% from reactions carried out
Highly enantioselective cyanosilylation of ketones catalyzed by a bifunctional Ti(IV) complex
Shen, Ke,Liu, Xiaohua,Li, Qinghan,Feng, Xiaoming
, p. 147 - 153 (2008)
A bifunctional catalyst system composed of (S)-prolinamide (2a), titanium(IV) isopropoxide, and phenolic N-oxide (3f) exhibited high catalytic efficiency in the enantioselective cyanosilylation of ketones. In the presence of 2.5 mol % catalyst, a variety
