25539-14-4

Basic information

• Product Name: 3,5-Dimethylphenylphenyl ether
• Synonyms: (3,5-Dimethylphenyl)phenyl ether;1-Phenoxy-3,5-dimethylbenzene;3,5-Dimethylphenylphenyl ether;Phenyl 3,5-dimethylphenyl ether;Phenyl(3,5-dimethylphenyl) ether;Phenyl[3,5-dimethylphenyl] ether;1,3-dimethyl-5-phenoxybenzene
• CAS NO: 25539-14-4
• Molecular Formula: C₁₄H₁₄O
• Molecular Weight: 198.2604
• Mol File: 25539-14-4.mol
• Article Data: 51

Chemical Properties

• Boiling Point: 285.6°Cat760mmHg
• Flash Point: 121.3°C
• Appearance: /
• Density: 1.029g/cm³
• Vapor Pressure: 0.00478mmHg at 25°C
• Refractive Index: 1.56
• CAS DataBase Reference: 3,5-Dimethylphenylphenyl ether(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-Dimethylphenylphenyl ether(25539-14-4)
• EPA Substance Registry System: 3,5-Dimethylphenylphenyl ether(25539-14-4)

Safety Data

• Hazardous Substances Data: 25539-14-4(Hazardous Substances Data)

Usage

General Description

3,5-Dimethylphenylphenyl ether, also known as bis(3,5-dimethylphenyl) ether, is a chemical compound with the molecular formula C14H14O. It is a colorless to pale yellow liquid with a faint floral odor. This ether is commonly used as a heat transfer fluid and as a solvent in various industrial processes. It is also utilized as a chemical intermediate in the production of pharmaceuticals, dyes, and perfumes. Additionally, it has applications in the synthesis of polymers and as a reagent in organic chemistry reactions. 3,5-Dimethylphenylphenyl ether exhibits low acute toxicity and has not been found to cause significant adverse effects on human health or the environment when used in accordance with safety guidelines.

InChI:InChI=1/C14H14O/c1-11-8-12(2)10-14(9-11)15-13-6-4-3-5-7-13/h3-10H,1-2H3

Upstream product

• 556-96-7 5-bromo-1,3-xylene 
• 108-95-2 phenol 
• 22445-41-6 3,5-dimethylphenyl iodide 
• 108-90-7 chlorobenzene 
• 108-68-9 3,5-Dimethylphenol 
• 591-50-4 iodobenzene 
• 3240-34-4 [bis(acetoxy)iodo]benzene 
• 98-80-6 phenylboronic acid 
• 603-33-8 triphenylbismuthane 
• 98-95-3 nitrobenzene 
• 172975-69-8 3,5-dimethylphenyl boronic acid 
• 108-86-1 bromobenzene 

Downstream Products

• 1610675-72-3 ethyl 2,6-dimethyl-4-phenoxyphenylphosphonamide 
• 1610675-92-7 5-phenoxy-7-methyl-1,2-dihydro-1-ethoxy-3H-2,1-benzazaphosphol-3-one 1-oxide 

Relevant articles and documents

Enhanced catalytic properties of copper in O- and N-arylation and vinylation reactions, using phosphorus dendrimers as ligands

Imino pyridine-capped phosphorus dendrimers were found to strongly enhance the catalytic activity of copper in arylations and vinylations of O- and N-nucleophiles. These reactions could indeed be performed under very mild conditions, often the mildest to

Ligand- and Counterion-Assisted Phenol O-Arylation with TMP-Iodonium(III) Acetates

High reactivity of trimethoxyphenyl (TMP)-iodonium(III) acetate for phenol O-arylation was achieved. It was first determined that the TMP ligand and acetate anion cooperatively enhance the electrophilic reactivity toward phenol oxygen atoms. The proposed method provides access to various diaryl ethers in significantly higher yields than the previously reported techniques. Various functional groups, including aliphatic alcohol, boronic ester, and sterically hindered groups, were tolerated during O-arylation, verifying the applicability of this ligand- and counterion-assisted strategy.

Ligand compound for copper catalyzed aryl halide coupling reaction, catalytic system and coupling reaction

The invention provides a ligand compound capable of being used for copper catalyzed aryl halide coupling reaction, the ligand compound is a three-class compound containing a 2-(substituted or non-substituted) aminopyridine nitrogen-oxygen group, and the invention also provides a catalytic system for the aryl halide coupling reaction. Thecatalytic system comprises a copper catalyst, a compound containing a 2-(substituted or non-substituted) aminopyridine nitrogen-oxygen group adopted as a ligand, alkali and a solvent, and meanwhile, the invention also provides a system for the aryl halide coupling reaction adopting the catalyst system. The compound containing the 2-(substituted or non-substituted) aminopyridine nitrogen oxygen group can be used as the ligand for the copper catalyzed aryl chloride coupling reaction, and the ligand is stable under a strong alkaline condition and can well maintain catalytic activity when being used for the copper-catalyzed aryl chloride coupling reaction. In addition, the copper catalyst adopting the compound as the ligand can particularly effectively promote coupling of copper catalyzed aryl chloride and various nucleophilic reagents which are difficult to generate under conventional conditions, C-N, C-O and C-S bonds are generated, and numerous useful small molecule compounds are synthesized. Therefore, the aryl halide coupling reaction has a very good large-scale application prospect by adopting the copper catalysis system of the ligand.

CoII Immobilized on Aminated Magnetic-Based Metal–Organic Framework: An Efficient Heterogeneous Nanostructured Catalyst for the C–O Cross-Coupling Reaction in Solvent-Free Conditions

Abstract: In this paper, we report the synthesis of Fe3O4?AMCA-MIL53(Al)-NH2-CoII NPs based on the metal–organic framework structures as a magnetically separable and environmentally friendly heterogeneous nanocatalyst. The prepared nanostructured catalyst efficiently promotes the C–O cross-coupling reaction in solvent-free conditions without the need for using toxic solvents and/or expensive palladium catalyst. Graphic Abstract: [Figure not available: see fulltext.].