25859-52-3

Upstream product

• 113665-70-6 π-methallyl palladium chloride 
• 107-31-3 Methyl formate 
• 67-56-1 methanol 
• 1458-98-6 2-methyl-3-bromo-1-propene 
• 108-59-8 malonic acid dimethyl ester 

Downstream Products

• 924-50-5 Methyl 3,3-dimethylacrylate 
• 56830-25-2 β-methoxy-isovaleric acid methyl ester 
• 763-32-6 2-methyl-1-buten-4-ol 
• 124744-25-8 methyl 2-methyloxiranylacetate 
• 535-80-8 3-chlorobenzoate 
• 556-24-1 methyl 3-methylbutanoate 
• 781-03-3 isopentenyl tosylate 
• 73214-63-8 7-methyl-3-methylene-7-octenyl propionate 
• 94916-02-6 3-Amino-3-methoxycarbonylmethyl-buttersaeure-anilid-N-sulfonyl-anilid 

Relevant academic research and scientific papers

Dimethyl malonate/LHMDS system as a new protocol for generating methyl formate anion (-COOMe) in the condensed-phase Dedicated to Professor Charles H. DePuy (1927-2013)

The treatment of dimethyl malonate with LHMDS in anhydrous THF (condensed-phase) generates, in addition to the expected corresponding lithium enolate, methyl formate anion (or methoxycarbonyl anion, -COOMe) which can react with several electrophiles to give corresponding methoxycarbonyl derivatives by nucleophilic substitution reaction.

Reactions of π-allylic complexes of palladium with methyl formate

The reaction of methyl formate with various π-allylic palladium complexes is reported. Unsaturated carboxylic acid esters are formed in high yield and selectivity. A comparison of the reactivity of methyl formate with that of the hydroesterification subst